In the realm of psychiatric pharmaceuticals, Olanzapine stands out as a crucial atypical antipsychotic. Its efficacy in managing schizophrenia and bipolar disorder makes it a cornerstone medication for millions worldwide. For professionals in the pharmaceutical industry, a thorough understanding of Olanzapine's properties, applications, and the importance of sourcing from reliable manufacturers is essential. This guide, brought to you by NINGBO INNO PHARMCHEM CO.,LTD., a leading supplier of pharmaceutical intermediates, aims to provide comprehensive insights.

Olanzapine: Chemical Profile and Therapeutic Action

Olanzapine (CAS No. 132539-06-1) is chemically known as 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine. It is typically supplied as a yellow crystalline powder with high purity, often exceeding 99%. Its therapeutic action is attributed to its antagonistic effects on dopamine D2 and serotonin 5-HT2A receptors, among others. This dual action differentiates it from older antipsychotics and contributes to its effectiveness with a generally lower incidence of certain side effects, such as extrapyramidal symptoms.

The pharmacological profile of Olanzapine also includes interactions with histamine H1, muscarinic M1, and alpha-1 adrenergic receptors, which can contribute to its side-effect profile, such as sedation and dry mouth. However, its efficacy in treating complex conditions remains significant.

Key Applications and Benefits of Olanzapine

Olanzapine is primarily indicated for:

  • Schizophrenia: It is highly effective in managing the positive symptoms (e.g., hallucinations, delusions) and negative symptoms (e.g., apathy, social withdrawal) of schizophrenia, improving patients' overall quality of life.
  • Bipolar Disorder: Olanzapine is used to treat acute manic or mixed episodes associated with bipolar I disorder, and as a maintenance treatment. It also plays a role in combination therapy for bipolar depression.
  • Other Uses: Off-label applications include the management of chemotherapy-induced nausea and vomiting, and as an appetite stimulant in specific patient populations.

The drug is generally well-absorbed orally and is metabolized in the liver. Its availability in various forms, including oral tablets and orally disintegrating tablets, caters to different patient needs.

Why Choose NINGBO INNO PHARMCHEM CO.,LTD. for Olanzapine API?

For pharmaceutical manufacturers and formulators, securing a consistent supply of high-quality Olanzapine API is critical. NINGBO INNO PHARMCHEM CO.,LTD. is a trusted manufacturer and supplier from China, offering distinct advantages:

  • Superior Quality Assurance: We guarantee the purity and quality of our Olanzapine, ensuring it meets rigorous pharmaceutical standards. This is vital for the safety and efficacy of the final drug product.
  • Competitive Pricing & Bulk Availability: As a direct manufacturer, we can offer competitive pricing for Olanzapine API, especially for bulk purchases. This allows our clients to manage costs effectively.
  • Reliable Supply Chain Management: We pride ourselves on a robust supply chain, ensuring timely delivery and consistent availability of Olanzapine, essential for uninterrupted production.
  • Technical & Regulatory Support: We provide comprehensive technical data and necessary regulatory documentation to facilitate your procurement and product development processes.

If your organization is looking to purchase Olanzapine or seeking a reliable Olanzapine supplier, NINGBO INNO PHARMCHEM CO.,LTD. is your ideal partner. We are committed to delivering excellence and supporting the global pharmaceutical industry. Contact us today to learn more and to request a quote or sample for our high-quality Olanzapine API.