Omeprazole Sulfone (CAS 88546-55-8) is more than just a synthetic precursor; it's a compound of significant interest in the realms of drug metabolism and analytical chemistry. For researchers studying the pharmacokinetics of omeprazole or developing robust analytical methods, understanding the roles of this metabolite is key. As a leading supplier of specialized fine chemicals, we provide high-quality Omeprazole Sulfone to support these critical scientific endeavors.

Understanding Drug Metabolism: Omeprazole, a widely used proton pump inhibitor, undergoes extensive metabolism in the body, primarily mediated by cytochrome P450 enzymes, particularly CYP2C19 and CYP3A4. Omeprazole Sulfone is identified as a major metabolic product formed through the sulfoxidation of omeprazole or esomeprazole. Studying Omeprazole Sulfone allows researchers to:

  • Investigate metabolic pathways and identify key enzymes involved.
  • Understand inter-individual variability in drug response due to genetic polymorphisms in metabolizing enzymes (e.g., CYP2C19 poor vs. extensive metabolizers).
  • Assess potential drug-drug interactions where other substances might inhibit or induce the metabolism of omeprazole, affecting the levels of its metabolites like Omeprazole Sulfone.
  • Gain insights into the efficacy and safety profiles of omeprazole formulations.

High-purity Omeprazole Sulfone is essential for accurate in vitro and in vivo metabolic studies. We supply this compound to researchers worldwide, ensuring reliable data generation.

Applications in Analytical Chemistry: In pharmaceutical quality control and research, Omeprazole Sulfone plays a vital role as an analytical standard. Its applications include:

  • Reference Standard for Impurity Testing: Pharmaceutical manufacturers use Omeprazole Sulfone as a certified reference material to quantify and qualify this specific impurity in omeprazole API and finished drug products. This is crucial for meeting regulatory standards.
  • Method Development and Validation: Analytical chemists employ Omeprazole Sulfone when developing and validating chromatographic methods (e.g., HPLC, LC-MS) for the detection and quantification of omeprazole and its related substances in biological matrices or pharmaceutical formulations.
  • Pharmacokinetic Analysis: In clinical and preclinical studies, measured levels of Omeprazole Sulfone in biological samples (plasma, urine) provide critical information about the absorption, distribution, metabolism, and excretion (ADME) of omeprazole.

As a trusted supplier, we understand the critical need for well-characterized and high-purity Omeprazole Sulfone for these applications. Whether you are investigating metabolic pathways or ensuring product quality, our product is manufactured to meet your exacting requirements. If you need to buy Omeprazole Sulfone for your research or analytical needs, we are your reliable source. Contact us to learn more about our product specifications and availability.