Optical Resolution with (1S,2S)-DPEN: Achieving Enantiopurity
In the quest for enantiopure compounds, a cornerstone of modern pharmaceutical and fine chemical synthesis, optical resolution stands as a vital technique. This method allows for the separation of a racemic mixture into its constituent enantiomers, ensuring that only the desired stereoisomer is utilized. Central to many successful optical resolution strategies is the use of chiral resolving agents, and (1S,2S)-1,2-Diphenylethane-1,2-diamine ((1S,2S)-DPEN) is a prime example of such a compound. As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM is dedicated to providing chemists with the high-quality intermediates necessary for these precise separations.
(1S,2S)-DPEN, with its well-defined chiral structure, is adept at forming diastereomeric derivatives or salts with racemic compounds. When a racemic mixture of an acidic or basic compound is treated with optically pure (1S,2S)-DPEN, the resulting diastereomers possess different physical properties, such as solubility and melting point. This difference is what enables their separation, typically through fractional crystallization. Once the diastereomers are isolated, the resolving agent can be cleaved off, yielding the individual enantiomers of the target compound in high purity.
The effectiveness of (1S,2S)-DPEN as a resolving agent is directly linked to its own enantiomeric purity. Our commitment as a manufacturer means that we supply (1S,2S)-1,2-Diphenylethane-1,2-diamine with an enantiomeric excess (e.e.) of u226599%. This high e.e. is crucial, as it directly translates to the potential purity of the resolved enantiomers. For procurement professionals and R&D scientists looking to buy this resolving agent, understanding these specifications is key to optimizing their resolution processes.
The applications for DPEN in optical resolution are widespread, particularly in the synthesis of chiral drugs where one enantiomer may possess therapeutic activity while the other is inactive or even detrimental. By leveraging a reliable supplier for (1S,2S)-DPEN, chemical manufacturers can ensure consistent and efficient production of enantiopure pharmaceuticals. We offer competitive pricing and readily available stock for this essential compound, making it an accessible tool for both laboratory-scale research and industrial-scale production.
To successfully implement optical resolution strategies, securing a dependable source for your chiral resolving agents is paramount. NINGBO INNO PHARMCHEM serves as that trusted partner, providing high-purity (1S,2S)-1,2-Diphenylethane-1,2-diamine from a reputable manufacturer. We invite you to request a quote and discuss your specific optical resolution needs. Partner with us to achieve the enantiopurity required for your most critical chemical syntheses.
Perspectives & Insights
Molecule Vision 7
“We offer competitive pricing and readily available stock for this essential compound, making it an accessible tool for both laboratory-scale research and industrial-scale production.”
Alpha Origin 24
“To successfully implement optical resolution strategies, securing a dependable source for your chiral resolving agents is paramount.”
Future Analyst X
“NINGBO INNO PHARMCHEM serves as that trusted partner, providing high-purity (1S,2S)-1,2-Diphenylethane-1,2-diamine from a reputable manufacturer.”