For professionals in the chemical and pharmaceutical industries, the strategic sourcing of raw materials is foundational to innovation and operational efficiency. 2-Bromo-4'-methoxyacetophenone, identified by its CAS number 2632-13-5, stands out as a critical intermediate. Understanding its properties, applications, and how to procure it effectively from leading suppliers is key to optimizing synthesis processes.

The Chemical Profile of 2-Bromo-4'-methoxyacetophenone

This compound is characterized by its molecular formula C9H9BrO2 and a molecular weight of approximately 229.07 g/mol. Its appearance is typically described as a light brown powder, with a melting point ranging from 69-71°C. The reactivity of the alpha-bromine atom makes it an excellent electrophile, readily participating in nucleophilic substitution reactions. This inherent reactivity is what makes 2-Bromo-4'-methoxyacetophenone an indispensable tool in modern organic synthesis.

Applications Driving Demand

The primary application of 2-Bromo-4'-methoxyacetophenone is as a vital intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). It serves as a crucial building block for creating complex molecular structures that form the basis of many modern medicines. Beyond pharmaceuticals, it finds utility in the broader field of fine chemical production and research and development, where its specific functional groups allow for the construction of diverse organic compounds. Whether used in Grignard reactions, alkylations, or cyclization processes, its consistent quality ensures predictable outcomes for manufacturers.

Sourcing Strategies for Procurement Managers

Procurement managers often seek to buy 2-Bromo-4'-methoxyacetophenone from suppliers who can guarantee not only high purity but also stable supply and competitive pricing. Key attributes to look for in a supplier include:

  • Manufacturer Direct Supply: Partnering directly with a manufacturer, especially one based in China, can significantly reduce costs and improve lead times.
  • Quality Assurance: Verify that the supplier provides comprehensive Certificates of Analysis (CoA) and adheres to strict quality control measures, such as HPLC analysis for purity.
  • Capacity and Reliability: Ensure the supplier has the production capacity to meet your volume requirements and a track record of dependable delivery.
  • Regulatory Compliance: For pharmaceutical applications, ensuring the supplier's compliance with relevant regulatory standards is crucial.

By establishing a strong relationship with a reputable manufacturer of 2-Bromo-4'-methoxyacetophenone (CAS 2632-13-5), companies can ensure a consistent flow of high-quality material. This not only supports seamless production cycles but also contributes to the overall cost-effectiveness and quality of the final products. Investing in reliable chemical intermediates is a strategic move that pays dividends in the competitive landscape of chemical manufacturing.