In the realm of chemical synthesis, understanding the precise properties and applications of key intermediates is vital for optimizing processes and achieving desired outcomes. CAS number 112022-83-0 refers to 1-Methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole, a compound of significant importance, particularly within the pharmaceutical industry. This article explores the chemical characteristics of this compound, its primary uses, and guides researchers and procurement specialists on how to effectively locate and buy it from reputable sources, emphasizing the benefits of working with manufacturers who offer competitive pricing.

1-Methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole, identified by CAS 112022-83-0 (and its isomer CAS 112022-81-8), is a sophisticated organoboron compound. Its primary function is as a chiral catalyst in asymmetric synthesis. This means it facilitates reactions where a specific stereoisomer is preferentially formed, a capability that is absolutely critical in the production of many pharmaceuticals. For instance, it is instrumental in the synthesis of ezetimibe analogs, which are key components in cholesterol-lowering medications. The typical purity level for this reagent is 95%+, ensuring reliable and predictable reaction outcomes for scientists.

For professionals involved in chemical procurement or R&D, identifying reliable suppliers for compounds like CAS 112022-83-0 is a continuous challenge. The global market offers numerous options, but discerning genuine, high-quality manufacturers is key. Many leading chemical synthesis companies are located in China, a region that has become a powerhouse for producing specialized intermediates and catalysts. When searching for this compound, look for suppliers that can provide detailed technical data, including its melting point (115-117°C), boiling point (111°C), and density (0.93 g/mL at 20°C). These parameters are crucial for chemists to integrate the reagent into their specific synthetic protocols.

When considering the price of 1-Methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole, it is advisable to obtain quotes from multiple manufacturers. Bulk purchase agreements often lead to significant cost reductions, making it more feasible for larger R&D projects or commercial production. Furthermore, partnering with a manufacturer that offers a stable supply chain and consistent product quality can prevent costly delays and ensure the smooth progression of your research or manufacturing operations.

In conclusion, understanding the chemical details and applications of CAS 112022-83-0 is essential for chemists and procurement specialists. By diligently researching and engaging with reputable manufacturers and suppliers, especially those based in China, one can secure this vital chiral catalyst at a competitive price, thereby optimizing chemical synthesis and advancing pharmaceutical development.