In the dynamic field of pharmaceutical research and development, the strategic incorporation of fluorine atoms into organic molecules has emerged as a powerful tool to modulate pharmacokinetic and pharmacodynamic properties. Fluorinated amino acids, such as L-3,4-Difluorophenylalanine, represent a significant class of compounds offering unique advantages in drug design. As a dedicated manufacturer and supplier of high-purity intermediates, NINGBO INNO PHARMCHEM CO.,LTD. recognizes the growing demand for these specialized building blocks.

L-3,4-Difluorophenylalanine (CAS: 31105-90-5) is a derivative of the natural amino acid phenylalanine, with two fluorine atoms strategically placed on the phenyl ring. This modification imparts several key benefits. Firstly, the strong electronegativity of fluorine can alter the electronic distribution within a molecule, influencing its binding affinity to biological targets. Secondly, the carbon-fluorine bond is one of the strongest single bonds in organic chemistry, which can enhance the metabolic stability of a drug candidate, leading to a longer half-life and potentially reduced dosing frequency. This makes it an invaluable component for R&D scientists seeking to develop more robust and effective therapeutics.

Furthermore, the introduction of fluorine can modify the lipophilicity of a compound, impacting its absorption, distribution, metabolism, and excretion (ADME) profile. This fine-tuning of physicochemical properties is crucial for optimizing drug candidates for oral bioavailability and target tissue penetration. For product formulation scientists, understanding these impacts is key to developing stable and effective drug products. We, as a leading manufacturer in China, provide detailed specifications to aid in your formulation process.

The applications of L-3,4-Difluorophenylalanine extend across various areas of drug discovery. It is frequently employed in the synthesis of peptidomimetics, where it can mimic or enhance the properties of natural peptides. Its use in protein engineering allows researchers to probe the role of specific amino acid residues in protein structure and function. For procurement managers, sourcing high-quality L-3,4-Difluorophenylalanine from a reliable supplier is paramount. We offer competitive pricing and ensure that our products meet stringent purity standards (typically 97% min), providing the confidence needed to purchase for critical research projects.

We understand that reliable supply chains are essential for the fast-paced pharmaceutical industry. NINGBO INNO PHARMCHEM CO.,LTD. is committed to being a dependable manufacturer and supplier, ensuring that your need to buy L-3,4-difluorophenylalanine is met with efficiency and professionalism. Whether you require small quantities for initial screening or larger volumes for preclinical studies, we offer flexible packaging and worldwide delivery. Feel free to request a quote for L-3,4-difluorophenylalanine from our expert sales team and discover the advantages of partnering with a leading chemical supplier.