For procurement managers in the pharmaceutical and fine chemical industries, securing high-quality intermediates is paramount to the success of R&D and manufacturing processes. One such critical intermediate is 2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl Bromide (CAS: 3068-32-4). Understanding its properties, applications, and reliable sourcing channels can significantly impact project timelines and budgets. As a leading manufacturer and supplier in China, we aim to provide clarity on procuring this vital glycosylation reagent.

Understanding the Intermediate: What is 2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl Bromide?

This compound is a highly acetylated derivative of galactose, featuring a reactive bromide atom. Its chemical formula is C14H19BrO9, with a molecular weight of approximately 411.2 g/mol. Typically appearing as a white crystalline solid, it melts in the range of 83-85°C. Its significance lies in its role as a glycosyl donor, a fundamental component in the synthesis of complex carbohydrates, glycoconjugates, and various biologically active molecules. For researchers in glycochemistry and drug discovery, its availability and purity are non-negotiable.

Key Applications Driving Demand

The primary application of this galactose derivative is in glycosylation reactions. These reactions are crucial for attaching carbohydrate moieties to other molecules, such as proteins, lipids, or small molecules. This process is fundamental in:

  • Pharmaceutical Development: Synthesizing complex oligosaccharides, glycoproteins, and glycolipids that are vital for many therapeutic agents, including vaccines, anticancer drugs, and antibiotics.
  • Organic Synthesis: Acting as a versatile building block for creating novel organic compounds with specific structural and functional properties.
  • Glycobiology Research: Facilitating the study of biological processes involving carbohydrates, such as cell recognition and signaling.

The ability to reliably buy this intermediate from a reputable supplier is key for continuous research and development.

Procurement Strategies for Procurement Managers

When sourcing 2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl Bromide, procurement managers should focus on several critical factors:

  1. Supplier Reliability: Partnering with established manufacturers in China who have a proven track record in producing high-purity fine chemicals is essential. Look for suppliers with strong quality control systems and certifications.
  2. Product Purity: While specifications vary, a purity of 97% or higher is generally preferred for advanced synthetic applications. Always request Certificates of Analysis (CoA) to verify lot-specific quality.
  3. Pricing and Bulk Orders: Competitive pricing is a significant consideration, especially for large-scale production. Negotiate terms for bulk purchases and explore potential cost savings. Enquire about sample availability to test quality before committing to larger orders.
  4. Lead Times and Logistics: Understanding lead times for manufacturing and shipping is crucial for maintaining project timelines. A responsive supplier will provide clear delivery estimates and efficient logistics solutions.

By focusing on these aspects, procurement professionals can ensure a consistent and cost-effective supply of this vital chemical intermediate. When you need to purchase this product, prioritizing a reputable manufacturer will safeguard your project's success.