In the rapidly advancing fields of drug delivery and biotechnology, liposomes and lipid nanoparticles (LNPs) have emerged as critical platforms. Their efficacy often hinges on the precise composition of their lipid bilayer. Among the key lipid components, phosphatidic acid (PA) plays a pivotal role due to its unique headgroup and amphipathic nature. Specifically, 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate monosodium salt (POPA sodium salt), with its well-defined structure and high purity, is an invaluable raw material for researchers and formulators aiming to optimize LNP performance. We are a premier manufacturer and supplier of this essential biomaterial in China, dedicated to providing the quality needed for cutting-edge applications.

POPA sodium salt is characterized by a saturated palmitoyl chain at the sn-1 position and an unsaturated oleoyl chain at the sn-2 position, attached to a glycerol backbone, with a phosphate group and a sodium counterion. This specific structure contributes to specific physicochemical properties that are beneficial in LNP formulation. Its ability to modulate membrane curvature and influence membrane fusion makes it a functional excipient rather than just a structural component. For scientists looking to buy high purity phosphatidic acid, sourcing from a reliable supplier is paramount to ensure reproducible results in their experimental setups.

The incorporation of POPA sodium salt into liposomal formulations can significantly impact the stability, charge, and cellular interaction of the resulting vesicles. For instance, its anionic nature can help stabilize negatively charged liposomes, which can be advantageous for specific therapeutic targeting or for reducing aggregation. Furthermore, PA is involved in various intracellular signaling pathways, suggesting potential synergistic effects when used in drug delivery systems designed for targeted cellular uptake or intracellular release. When you choose to purchase from us, a leading chemical supplier, you are assured of a product that meets stringent quality standards, typically boasting a purity of ≥98.0% via HPLC.

As a leading supplier in China, we understand the critical need for consistent quality and reliable supply chains in the pharmaceutical and biotech industries. Whether you are involved in early-stage research, preclinical development, or scaling up for commercial production, our POPA sodium salt is manufactured to support your objectives. We offer competitive pricing for this crucial lipid intermediate, making it accessible for various project scales. If you are in need of a trusted manufacturer for your lipid raw materials, consider us for your sourcing needs. We provide readily available samples and detailed technical support to facilitate your procurement process.

To effectively utilize POPA sodium salt, researchers often explore its synergistic effects with other lipids, such as cholesterol, phospholipids, and ionizable lipids, to achieve desired particle size, encapsulation efficiency, and in vivo performance. Experimentation with varying molar ratios of POPA sodium salt can lead to optimized liposomal formulations for specific applications, be it gene therapy, vaccine delivery, or targeted chemotherapy. We encourage you to reach out to us to buy this high-grade lipid or to request a quote for bulk orders. Our commitment as a global supplier is to empower scientific innovation by providing essential, high-quality chemical intermediates.