For chemists engaged in complex organic synthesis, the availability of reliable and high-quality building blocks is fundamental to achieving successful outcomes. 4-Methylsulphonylphenylacetic Acid, identified by CAS 90536-66-6, is one such compound that offers significant utility. Its structure, featuring both a sulfonyl group and a carboxylic acid moiety, makes it a versatile reactant for a wide array of chemical transformations. Understanding its properties and applications can help R&D scientists and procurement managers optimize their synthetic strategies.

The chemical properties of 4-Methylsulphonylphenylacetic Acid are key to its broad applicability. Typically appearing as a white to pale yellow crystalline solid with a melting point around 136-140 °C, it exhibits slight solubility in water but better solubility in solvents like DMSO and methanol. Its pKa of approximately 3.90 indicates it is a moderately strong organic acid. These characteristics are vital for chemists to consider when designing reaction conditions, choosing solvents, and predicting reactivity. For instance, its acidic nature allows it to participate in esterification or amidation reactions readily, while the methylsulfonyl group can influence the electronic properties of the aromatic ring, impacting electrophilic or nucleophilic aromatic substitution reactions.

In terms of applications, 4-Methylsulphonylphenylacetic Acid serves as a crucial intermediate in various fields, including pharmaceuticals, agrochemicals, and dyestuffs. Its most notable use is in the synthesis of pharmaceutical compounds, particularly as a precursor to selective COX-2 inhibitors and antioxidants. Researchers utilize its structure to build complex heterocyclic diaryl compounds or to incorporate specific functional groups that impart desired biological activity. The demand for this intermediate highlights its importance in developing advanced materials and active pharmaceutical ingredients (APIs).

When sourcing this essential compound, choosing a reliable manufacturer and supplier is critical. We, as a leading chemical supplier based in China, specialize in providing high-purity 4-Methylsulphonylphenylacetic Acid. Our extensive experience in chemical synthesis and production ensures that the material you purchase meets your exacting standards. We understand that for many R&D projects, securing a consistent and affordable supply is a primary concern. Therefore, we offer competitive pricing for bulk orders and are committed to providing exceptional customer service. If you are looking to buy 4-Methylsulphonylphenylacetic Acid for your ongoing synthesis projects, our facility is equipped to meet your needs.

For procurement professionals, the ability to obtain materials like 4-Methylsulphonylphenylacetic Acid (CAS 90536-66-6) with confidence is essential. We provide detailed technical specifications and are available to answer any questions regarding its handling, storage, and reactivity. Our goal is to be more than just a supplier; we aim to be a partner in your research and development endeavors. We invite you to contact us to request a quote and to learn more about our product offerings and supply capabilities.

In summary, 4-Methylsulphonylphenylacetic Acid is a highly valuable intermediate in organic synthesis, offering diverse applications in the pharmaceutical and chemical industries. As a reputable China manufacturer and supplier, we are dedicated to providing consistent quality and competitive pricing for this critical compound. Engage with us to ensure your organic synthesis projects are supported by reliable, high-purity 4-Methylsulphonylphenylacetic Acid.