For organic chemists engaged in research and development, the selection of versatile building blocks is crucial for efficient and innovative synthesis. 3-Aminobenzonitrile (CAS 2237-30-1), also known as m-cyanoaniline, is a prime example of such a compound, offering a unique combination of reactive functionalities that open doors to a wide array of chemical transformations. As a dedicated supplier and manufacturer of fine chemicals from China, we aim to empower chemists by providing access to high-quality 3-aminobenzonitrile and sharing insights into its optimized use.

Harnessing the Reactivity of 3-Aminobenzonitrile

The dual nature of 3-aminobenzonitrile, possessing both an amine and a nitrile group, makes it a highly sought-after intermediate. The amino group can undergo acylation, alkylation, and diazotization reactions, serving as a nucleophile or a handle for further functionalization. Meanwhile, the nitrile group is a precursor to carboxylic acids, amides, and tetrazoles, and can participate in cycloaddition reactions. This dual reactivity allows for the construction of complex heterocyclic systems, aromatic amines, and other valuable organic molecules that are integral to many research and industrial processes.

Key Synthetic Transformations and Applications

Chemists frequently utilize 3-aminobenzonitrile in reactions such as:

  • Diazotization and Coupling: The amine group can be diazotized and subsequently coupled with activated aromatic compounds to form azo dyes or used in Sandmeyer-type reactions to introduce halogens or other groups.
  • Condensation Reactions: It readily undergoes condensation reactions with carbonyl compounds to form imines or Schiff bases, which can be further reduced or cyclized.
  • Nitrile Hydrolysis/Reduction: The nitrile group can be hydrolyzed to a carboxylic acid or reduced to an amine, expanding the synthetic utility significantly.
  • Heterocycle Synthesis: Its structure is well-suited for forming benzimidazoles, quinazolines, and other nitrogen-containing heterocycles, which are prevalent in pharmaceuticals and agrochemicals.

When seeking to buy 3-aminobenzonitrile for these applications, it is essential to consider the purity and physical form. We ensure our product is consistently available as a fine white powder with high purity, facilitating its seamless integration into your synthetic schemes. Understanding the current price of 3-aminobenzonitrile from reputable suppliers is also key to cost-effective research.

Sourcing m-Cyanoaniline: Tips for Chemists

As a direct manufacturer, we recommend several best practices when sourcing 3-aminobenzonitrile:

  • Verify Purity: Always request a Certificate of Analysis (CoA) to confirm the purity and identity of the compound. For demanding syntheses, a purity of 98% or higher is typically preferred.
  • Consider Quantity: Whether you need gram-scale quantities for initial exploration or kilogram-scale for pilot studies, ensure your supplier can accommodate your needs. We offer flexible ordering options for CAS 2237-30-1.
  • Supplier Reliability: Partner with a supplier known for consistent quality, timely delivery, and responsive customer service. Our commitment as a China-based manufacturer means we focus on building long-term relationships with our clients.
  • Safety First: Always consult the Safety Data Sheet (SDS) for proper handling, storage, and disposal procedures for 3-aminobenzonitrile.

By understanding the chemical properties and sourcing effectively, chemists can fully leverage the potential of 3-aminobenzonitrile in their organic synthesis endeavors. We are committed to providing the chemical community with the high-quality materials needed to drive innovation.