In the intricate world of peptide synthesis, selecting the right building blocks is paramount to achieving successful outcomes. Among these crucial components, protected amino acids play a vital role, ensuring that complex peptide chains are assembled with precision and purity. One such indispensable derivative is Boc-D-His(Tos)-OH·DCHA, a compound that has become a staple for researchers and manufacturers alike.

Boc-D-His(Tos)-OH·DCHA, chemically known as N-cyclohexylcyclohexanamine; (2S)-3-[1-(4-methylphenyl)sulfonylimidazol-4-yl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid, offers a unique combination of protecting groups that are essential for controlled peptide chain elongation. The tert-butoxycarbonyl (Boc) group protects the alpha-amino group, while the tosyl (p-toluenesulfonyl) group safeguards the imidazole ring of histidine. This dual protection strategy is critical in solid-phase peptide synthesis (SPPS), preventing unwanted side reactions and ensuring that the histidine residue is incorporated correctly into the growing peptide sequence.

As a leading manufacturer and supplier of fine chemical intermediates in China, we understand the stringent requirements of the pharmaceutical and biotechnology sectors. Our commitment to producing high-purity Boc-D-His(Tos)-OH·DCHA (typically ≥98%) ensures that our clients receive a product that meets rigorous quality standards. This focus on purity is not merely a technical specification; it directly impacts the success of complex synthesis projects, from early-stage research to the production of peptide-based therapeutics.

The D-configuration of histidine in this derivative also opens doors to synthesizing peptides with specific stereochemistry, which can significantly influence their biological activity and stability. Whether you are developing novel peptide drugs, creating custom peptides for research, or optimizing existing synthesis protocols, sourcing your Boc-D-His(Tos)-OH·DCHA from a reliable supplier is key. We invite you to buy this essential amino acid derivative and experience the difference that quality and consistency can make. For those looking to purchase in bulk or inquire about pricing, our dedicated sales team is ready to assist.