Peptide synthesis is a cornerstone of modern biotechnology and pharmaceutical research, enabling the creation of therapeutic peptides, diagnostic tools, and research reagents. The selection of appropriate amino acid building blocks critically impacts the efficiency and success of these syntheses. Azetidine-3-Carboxylic Acid, a non-proteinogenic amino acid derivative, offers unique advantages that can significantly optimize peptide synthesis workflows. As a dedicated manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. provides researchers with access to this vital component.

Azetidine-3-Carboxylic Acid, appearing as a fine white to off-white powder with a purity often exceeding 97%, is prized for its distinct structural characteristics. The cyclic nature of the azetidine ring introduces rigidity into peptide backbones, which can be beneficial for several reasons. This conformational constraint can lead to enhanced binding affinity to target biomolecules, improved resistance to proteolytic degradation, and modified biological activity compared to linear analogs. Researchers frequently buy this compound to explore these effects.

In solid-phase peptide synthesis (SPPS), Azetidine-3-Carboxylic Acid can be incorporated using standard coupling protocols, often with appropriate Fmoc or Boc protection. Its successful integration requires high-quality reagents to ensure efficient coupling and minimal racemization. For scientists focused on therapeutic peptides, understanding the cost implications is vital, making competitive price inquiries to reliable manufacturers like us essential. Sourcing from China offers a strategic advantage for cost-effective procurement.

The applications of peptides incorporating Azetidine-3-Carboxylic Acid are broad and growing. They include the development of peptide-based drugs with improved pharmacokinetic profiles, the design of peptidomimetics that mimic natural peptide functions but with enhanced stability, and the creation of peptides for diagnostics and material science applications. The chemical industry’s ability to supply this intermediate consistently, as exemplified by NINGBO INNO PHARMCHEM CO.,LTD., underpins these advancements.

When you purchase Azetidine-3-Carboxylic Acid (CAS 36476-78-5), consider the following benefits for your peptide synthesis projects:

  • Conformational Control: Introduce specific turns or rigid structures into your peptide sequence.
  • Enhanced Stability: Improve resistance to enzymatic breakdown, leading to longer peptide half-lives.
  • Modulated Biological Activity: Fine-tune receptor binding or enzyme inhibition by altering peptide conformation.
  • Novel Peptide Architectures: Expand the repertoire of accessible peptide structures for drug discovery and research.

To ensure the highest quality for your peptide synthesis needs, partner with NINGBO INNO PHARMCHEM CO.,LTD. We are committed to providing top-tier Azetidine-3-Carboxylic Acid and supporting your research endeavors. Get a quote today and discover how our expertise can benefit your next peptide synthesis project.