In the intricate field of peptide synthesis, the selection of high-quality building blocks is paramount. Among these, Fmoc-D-3-Chlorophenylalanine stands out as a versatile and valuable protected amino acid derivative. For researchers and B2B procurement managers looking to optimize their peptide synthesis processes, understanding the advantages and applications of this compound is crucial. As a leading manufacturer and supplier of specialty chemicals, we provide insights into how this particular amino acid can elevate your research and development efforts.

Fmoc-D-3-Chlorophenylalanine, identified by CAS number 205526-23-4, combines the widely adopted Fmoc (9-fluorenylmethoxycarbonyl) protecting group with a D-phenylalanine core featuring a chlorine atom at the 3-position of the phenyl ring. The Fmoc group offers efficient protection of the amine terminus, crucial for controlled, stepwise chain elongation in Solid-Phase Peptide Synthesis (SPPS). Its selective removal under mild basic conditions allows for subsequent coupling reactions without damaging the growing peptide chain. This makes it an indispensable tool for synthesizing complex peptides, including those intended for therapeutic applications.

The introduction of a chlorine atom onto the phenyl side chain of phenylalanine is not merely a structural modification; it significantly influences the molecule's electronic properties and potentially its biological interactions. This makes Fmoc-D-3-Chlorophenylalanine particularly useful in Structure-Activity Relationship (SAR) studies. By comparing peptides incorporating this modified amino acid with their non-chlorinated counterparts, researchers can gain valuable insights into how specific structural features affect peptide conformation, stability, receptor binding, and overall biological activity. This is fundamental in the drug discovery process, where fine-tuning molecular structures is key to optimizing efficacy and minimizing side effects.

Moreover, the compound finds application in the development of peptide-based therapeutics. The tailored properties imparted by the chloro-phenylalanine moiety can lead to enhanced potency, improved metabolic stability, or altered pharmacokinetic profiles for peptide drugs. This makes it a sought-after building block for pharmaceutical companies and contract research organizations (CROs) engaged in developing next-generation therapeutics.

For B2B procurement managers, sourcing reliable, high-purity chemicals is a top priority. When you buy Fmoc-D-3-Chlorophenylalanine, ensuring its quality and consistent supply is critical for the reproducibility of your research and manufacturing processes. As a dedicated manufacturer and supplier in China, we pride ourselves on delivering premium-grade Fmoc-D-3-Chlorophenylalanine. Our commitment to quality control ensures that each batch meets stringent purity specifications, making us a trusted partner for your chemical needs. We offer competitive Fmoc-D-3-Chlorophenylalanine price points, especially for bulk orders, allowing research institutions and pharmaceutical companies to manage their budgets effectively while accessing top-tier materials.

In summary, Fmoc-D-3-Chlorophenylalanine is more than just a chemical reagent; it's a key enabler for cutting-edge research in peptide science and drug development. Its unique combination of Fmoc protection and the chlorine substituent provides researchers with a powerful tool for exploration and innovation. If you are looking to purchase Fmoc-D-3-Chlorophenylalanine for your peptide synthesis or drug discovery projects, consider partnering with a reliable supplier. We invite you to request a quote and discover how our commitment to quality and service can support your scientific endeavors.