The pharmaceutical industry is constantly seeking to enhance the efficiency and quality of Active Pharmaceutical Ingredient (API) synthesis. For manufacturers of Saxagliptin, a cornerstone medication for type 2 diabetes management, the quality of intermediate compounds is paramount. Among these, (1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide Methanesulfonate stands out as a critical building block.

This article delves into the significance of this specific intermediate and provides insights for procurement professionals and R&D scientists looking to buy (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate. Understanding its properties and the benefits of sourcing from a reputable pharmaceutical intermediate manufacturer in China can significantly impact your production workflow and end-product quality.

Understanding the Intermediate: Properties and Specifications

(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide Methanesulfonate, identified by CAS number 709031-45-8, is a vital component in the multi-step synthesis of Saxagliptin. Its chemical structure and purity directly influence the overall yield and efficacy of the final API. Key specifications to consider when sourcing this compound include:

  • Appearance: Typically presented as an off-white to light brown powder. Visual inspection can be an initial indicator of product integrity.
  • Assay: A high purity level, usually ≥97.0%, is essential to minimize unwanted by-products during synthesis and ensure the pharmaceutical-grade quality of Saxagliptin.
  • Molecular Formula & Weight: C7H14N2O4S, with a molecular weight of 222.262, critical for stoichiometric calculations in your reaction pathways.

Why Partner with a Chinese Manufacturer for Saxagliptin Intermediates?

Sourcing critical chemical intermediates from China has become a strategic advantage for many pharmaceutical companies. When looking for a saxagliptin intermediate supplier, consider the benefits of a well-established Chinese manufacturer like NINGBO INNO PHARMCHEM CO.,LTD.:

  • Cost-Effectiveness: Chinese chemical manufacturers often offer competitive pricing due to economies of scale and efficient production processes. This allows you to reduce overall API manufacturing costs when you purchase (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-3-carboxamide methanesulfonate.
  • Quality Assurance: Reputable manufacturers adhere to international quality standards, implementing rigorous quality control measures throughout the production cycle. This ensures you receive high-quality, consistent batches of the intermediate.
  • Supply Chain Stability: Partnering with a manufacturer with a proven track record in production and logistics provides a more secure and stable supply chain, reducing the risk of production delays.
  • Technical Expertise: Many Chinese suppliers possess strong R&D capabilities and can offer technical support, helping you optimize your synthesis processes.

Ensuring Quality and Reliability in Your Purchase

When you decide to buy CAS 709031-45-8 for sale, it is crucial to work with a supplier who can guarantee the quality and reliability of their product. Look for manufacturers who provide:

  • Certificates of Analysis (CoA) detailing purity and other critical parameters.
  • Detailed Safety Data Sheets (SDS).
  • Secure and compliant packaging (e.g., 25 kg/drum).
  • Appropriate storage conditions to maintain product integrity.

In conclusion, the availability of high-quality (1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide Methanesulfonate is fundamental for efficient and effective Saxagliptin synthesis. By selecting a trusted pharmaceutical intermediate supplier in China, you can ensure the quality, cost-effectiveness, and stability of your pharmaceutical manufacturing operations.