In the intricate world of pharmaceutical synthesis, the choice of intermediates plays a pivotal role in the efficiency, purity, and ultimate success of drug development. L-(+)-Glutamic Acid Hydrochloride (CAS 138-15-8) has emerged as a valuable pharmaceutical intermediate, particularly for compounds targeting the central nervous system. As a leading manufacturer and supplier of fine chemicals in China, we are committed to providing the pharmaceutical industry with high-quality, reliable intermediates.

The Chemical Profile of L-Glutamic Acid Hydrochloride

L-(+)-Glutamic Acid Hydrochloride is characterized by its chemical formula C5H10ClNO4 and a molecular weight of 183.59 g/mol. It appears as a white crystalline powder, with significant solubility in water (approximately 490 g/L at 20 ºC). This solubility, coupled with its inherent stability as a hydrochloride salt, makes it an ideal starting material or intermediate for complex organic syntheses. Its precise stereochemistry is crucial for many pharmaceutical applications where enantiomeric purity is paramount.

Key Roles in Pharmaceutical Synthesis

The significance of L-(+)-Glutamic Acid Hydrochloride in pharmaceutical synthesis stems from its structural relationship to glutamic acid, a major excitatory neurotransmitter in the brain. This allows it to be used in the synthesis of:

  • Neuroactive Compounds: It serves as a building block for agonists and antagonists of glutamate receptors, vital in the research and development of treatments for neurological disorders such as epilepsy, Alzheimer's disease, and depression.
  • Peptide Synthesis: As an amino acid derivative, it can be incorporated into peptide chains, which are increasingly important in drug discovery for therapeutic peptides.
  • Diagnostic Reagents: Used in the creation of specific diagnostic agents that interact with biological systems related to glutamate pathways.

For R&D scientists and procurement managers, sourcing a pharmaceutical intermediate that guarantees purity and consistent enantiomeric excess is non-negotiable. When you buy L-(+)-Glutamic Acid Hydrochloride from our manufacturing facility, you are assured of a product that adheres to strict quality control measures, ensuring that your synthetic pathways are reliable and your final active pharmaceutical ingredients (APIs) meet the required standards.

Advantages of Sourcing from a Chinese Manufacturer

Our position as a manufacturer in China allows us to offer L-(+)-Glutamic Acid Hydrochloride at competitive prices, facilitating cost-effective drug development. We understand the critical nature of supply chain reliability in the pharmaceutical sector. Our production processes are designed for scalability, ensuring that we can meet demand from pilot-scale synthesis to large-scale commercial manufacturing. We invite pharmaceutical companies to partner with us for their intermediate needs.

We are prepared to provide detailed technical documentation, samples for evaluation, and comprehensive quotes for bulk purchases. If your synthesis requires a high-quality, reliable source of L-(+)-Glutamic Acid Hydrochloride, please reach out to our specialized sales team. We are dedicated to supporting your pharmaceutical innovation from concept to market.