Organic synthesis is a cornerstone of modern chemistry, enabling the creation of everything from life-saving medicines to advanced materials. Within this field, specific intermediates play critical roles, facilitating complex transformations. 5-Chloro-1,3-dimethoxybenzene (CAS 7051-16-3) is one such versatile compound, highly valued by chemists for its unique reactivity and applicability in constructing intricate molecular architectures.

Understanding the Chemical Properties of 5-Chloro-1,3-dimethoxybenzene

This compound, often recognized by its CAS number 7051-16-3, is typically supplied as a crystalline powder, usually white to yellow or pink, with a purity assay of ≥97.0%. Its molecular structure, a benzene ring substituted with a chlorine atom and two methoxy groups, dictates its chemical behavior. This arrangement makes it amenable to a variety of organic reactions, including electrophilic aromatic substitution and cross-coupling reactions. For any chemist looking to buy 5-chloro-1,3-dimethoxybenzene, understanding these properties is key to successful integration into synthetic schemes.

Key Reactions and Applications in Organic Synthesis:

  • Suzuki-Miyaura Cross-Coupling: A prominent application of 5-Chloro-1,3-dimethoxybenzene is its participation in Suzuki-Miyaura cross-coupling reactions. This palladium-catalyzed reaction allows for the efficient formation of carbon-carbon bonds by reacting aryl or vinyl halides with organoboron compounds. Its use in this context is invaluable for building complex aromatic systems.
  • Electrophilic Substitution: The presence of activating methoxy groups influences the regioselectivity of electrophilic aromatic substitution reactions, allowing chemists to precisely control where new substituents are introduced onto the aromatic ring.
  • Intermediate for Complex Molecules: As a building block, it is instrumental in the synthesis of pharmaceuticals, agrochemicals, and specialty organic materials. Its structure provides a functionalized aromatic core that can be further elaborated upon.
  • Research and Development: In R&D settings, this compound is used to explore new synthetic methodologies and to create novel chemical entities with potentially useful properties.

Sourcing and Quality for Synthesis Projects

For effective organic synthesis, sourcing high-quality intermediates is paramount. As a leading chemical supplier in China, we are a dedicated manufacturer of 5-Chloro-1,3-dimethoxybenzene, ensuring high purity (≥97.0%) and consistent batch-to-batch quality. We understand that reliable access to materials at a competitive price is crucial for project success. Therefore, we emphasize our role as a trustworthy partner for chemists and researchers.

If your work involves complex organic synthesis and you need to purchase 5-chloro-1,3-dimethoxybenzene, we encourage you to consider our offerings. We provide detailed technical data and are available to answer any questions regarding specifications or bulk orders for CAS 7051-16-3. Partner with us to ensure your synthesis projects have the reliable chemical building blocks they need.