Organic synthesis is the bedrock of innovation in chemical industries, from pharmaceuticals to advanced materials. At the heart of this discipline lie versatile chemical intermediates that enable the construction of complex molecular architectures. One such crucial compound is 2-Hydroxy-5-nitropyridine (CAS 5418-51-9), a pyridine derivative widely recognized for its utility as a building block. For chemists and researchers seeking to expand their synthetic capabilities, understanding the applications and sourcing of this intermediate is key.

Understanding 2-Hydroxy-5-Nitropyridine in Synthesis

2-Hydroxy-5-nitropyridine, typically appearing as a light yellow to light brown crystalline powder, is prized for its specific functional groups that allow for a wide range of chemical transformations. Its structure makes it an excellent starting material or intermediate in reactions designed to introduce nitro groups, hydroxyl groups, or pyridine rings into larger molecules. The compound's reliability in synthesis is often attributed to its high purity, with specifications commonly exceeding 99.0%. This consistency is vital for reproducibility in laboratory settings and scalability in industrial production. Whether you are developing new pharmaceuticals, agrochemicals, or specialized materials, this intermediate provides a robust platform for innovation.

Key Applications in Organic Synthesis

The versatility of 2-Hydroxy-5-nitropyridine is evident in its numerous applications:

  • Pharmaceutical Intermediate: Its primary role is as a precursor in the synthesis of various Active Pharmaceutical Ingredients (APIs). It is particularly useful in creating molecules with anti-inflammatory, antimicrobial, or anticancer properties. Chemists often leverage its structure to build complex heterocyclic systems common in drug design.
  • Agrochemical Development: In the agrochemical sector, 2-Hydroxy-5-nitropyridine serves as an intermediate for synthesizing pesticides and herbicides. Its inclusion can enhance the efficacy or target specificity of these agricultural products.
  • Material Science: Researchers explore its potential in developing novel materials, such as specialty polymers or functional coatings, where its chemical stability and reactive sites can be exploited.
  • As a Research Chemical: In academic and industrial research labs, it is a valuable reagent for exploring new synthetic methodologies, reaction mechanisms, and for creating chemical libraries used in high-throughput screening.

Sourcing and Purchasing Considerations

When you intend to buy 2-Hydroxy-5-nitropyridine, selecting the right supplier is critical. A dependable manufacturer will offer:

  • Guaranteed Purity: Ensure the product meets stringent purity standards (e.g., ≥ 99.0%) with comprehensive analytical documentation.
  • Scalable Supply: Whether for small-scale research or large-scale production, confirm the supplier can meet your volume needs.
  • Technical Support: Access to safety data sheets (SDS) and product specifications aids in safe handling and effective utilization.
  • Competitive Pricing: Obtain quotes from reliable suppliers, particularly those based in China, to ensure cost-effectiveness without compromising quality.

We are a premier supplier of high-quality chemical intermediates, including 2-Hydroxy-5-nitropyridine. Our commitment to excellence ensures that you receive a product that meets the highest standards for your organic synthesis needs. Contact us today to discuss your requirements and to purchase 2-Hydroxy-5-nitropyridine.