The Role of Ornithine Derivatives in Modern Peptide Chemistry
Ornithine, a non-proteinogenic amino acid, plays an increasingly significant role in peptide chemistry due to its unique structural features, especially the presence of an additional amino group on its side chain. This makes it a versatile component for creating peptides with enhanced properties or specific functionalities. However, to effectively incorporate ornithine into complex peptide structures, protective groups are indispensable. Among these, N-delta-Benzyloxycarbonyl-L-ornithine (H-Orn(Z)-OH) is a prime example of how strategic protection facilitates advanced peptide synthesis.
The benzyloxycarbonyl (Z or Cbz) protecting group on the delta-amino nitrogen of ornithine in H-Orn(Z)-OH (CAS 3304-51-6) offers a level of control that is critical in multi-step syntheses. This allows researchers to selectively react at the alpha-amino group or the carboxylic acid, while keeping the side chain’s amino group safely masked. This is particularly important when building intricate peptide sequences, ensuring that each amino acid is added in the correct order and without cross-reactivity. NINGBO INNO PHARMCHEM CO.,LTD. understands the importance of these specific derivatives for successful custom peptide synthesis.
The application of ornithine derivatives extends beyond simple peptide chain elongation. They are pivotal in the development of peptide-based drugs, diagnostics, and research tools. For instance, incorporating modified ornithine residues can influence a peptide’s pharmacokinetic properties, such as its stability against proteases or its interaction with biological targets. Understanding the various chemical properties of protected amino acids is key for researchers to leverage these benefits effectively.
As a reliable manufacturer and supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. offers a range of ornithine derivatives, including H-Orn(Z)-OH, to support the growing demands of the pharmaceutical and biotechnology sectors. The availability of these essential building blocks at competitive prices is crucial for advancing scientific discovery. Whether you are developing novel therapeutics or exploring fundamental biochemical pathways, the right ornithine derivative can make a significant difference in your research outcomes.
By providing high-quality H-Orn(Z)-OH and other essential amino acid derivatives, NINGBO INNO PHARMCHEM CO.,LTD. aims to be a cornerstone in the progress of peptide chemistry and its applications.
The benzyloxycarbonyl (Z or Cbz) protecting group on the delta-amino nitrogen of ornithine in H-Orn(Z)-OH (CAS 3304-51-6) offers a level of control that is critical in multi-step syntheses. This allows researchers to selectively react at the alpha-amino group or the carboxylic acid, while keeping the side chain’s amino group safely masked. This is particularly important when building intricate peptide sequences, ensuring that each amino acid is added in the correct order and without cross-reactivity. NINGBO INNO PHARMCHEM CO.,LTD. understands the importance of these specific derivatives for successful custom peptide synthesis.
The application of ornithine derivatives extends beyond simple peptide chain elongation. They are pivotal in the development of peptide-based drugs, diagnostics, and research tools. For instance, incorporating modified ornithine residues can influence a peptide’s pharmacokinetic properties, such as its stability against proteases or its interaction with biological targets. Understanding the various chemical properties of protected amino acids is key for researchers to leverage these benefits effectively.
As a reliable manufacturer and supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. offers a range of ornithine derivatives, including H-Orn(Z)-OH, to support the growing demands of the pharmaceutical and biotechnology sectors. The availability of these essential building blocks at competitive prices is crucial for advancing scientific discovery. Whether you are developing novel therapeutics or exploring fundamental biochemical pathways, the right ornithine derivative can make a significant difference in your research outcomes.
By providing high-quality H-Orn(Z)-OH and other essential amino acid derivatives, NINGBO INNO PHARMCHEM CO.,LTD. aims to be a cornerstone in the progress of peptide chemistry and its applications.
Perspectives & Insights
Logic Thinker AI
“offers a range of ornithine derivatives, including H-Orn(Z)-OH, to support the growing demands of the pharmaceutical and biotechnology sectors.”
Molecule Spark 2025
“The availability of these essential building blocks at competitive prices is crucial for advancing scientific discovery.”
Alpha Pioneer 01
“Whether you are developing novel therapeutics or exploring fundamental biochemical pathways, the right ornithine derivative can make a significant difference in your research outcomes.”