In the realm of chemical manufacturing and research, specific compounds serve as linchpins for innovation and production. 3,4-Dimethoxyphenylacetonitrile, known by its CAS number 93-17-4, is one such vital chemical intermediate. This comprehensive overview examines its properties, diverse industrial applications, synthesis pathways, and essential safety considerations, providing valuable insights for R&D scientists, formulators, and procurement managers.

Understanding the Compound: Properties and Identification

3,4-Dimethoxyphenylacetonitrile, also recognized by names like Homoveratronitrile or 3,4-dimethoxybenzyl cyanide, is an aromatic nitrile with the molecular formula C10H11NO2. It typically presents as a white to off-white crystalline solid, boasting a high purity of 99% or more. Its physical characteristics, including a melting point range of 54-57°C and solubility in organic solvents such as methanol, are critical for its handling and use in synthesis. For those looking to buy this compound, these specifications are the first point of reference for quality assessment.

Industrial Applications and Significance

The primary industrial value of 3,4-Dimethoxyphenylacetonitrile is its role as a key intermediate in the synthesis of pharmaceuticals. It is indispensable in the production of Cefuroxime, a vital broad-spectrum antibiotic. Furthermore, it is employed in the synthesis of other complex organic molecules and is identified as an impurity in Verapamil, a cardiovascular drug, highlighting its relevance in quality control and analytical chemistry. The compound's utility extends to general organic synthesis, where it acts as a versatile building block for creating more complex molecular structures with potential biological activities. Companies sourcing this chemical are often focused on drug discovery and the reliable manufacturing of APIs.

Synthesis and Manufacturing Excellence

The production of 3,4-Dimethoxyphenylacetonitrile involves specific chemical synthesis routes, often starting with O-dimethoxybenzene derivatives. Modern manufacturing processes aim for efficiency, high yield, and product purity through optimized reaction conditions and purification techniques. For businesses globally, sourcing from established manufacturers, particularly in China, provides access to high-quality materials produced at scale. A reputable supplier will adhere to strict quality control measures, ensuring batch-to-batch consistency, which is non-negotiable for pharmaceutical applications. When you purchase this intermediate, verify the supplier's commitment to quality and reliable delivery.

Safety, Handling, and Storage

As with any chemical intermediate, proper safety protocols are essential when handling 3,4-Dimethoxyphenylacetonitrile. While specific hazard information should always be consulted from the Safety Data Sheet (SDS), general precautions include avoiding contact with skin, eyes, and clothing, and ensuring adequate ventilation. It is typically stored in a cool, dry place, away from incompatible materials, to maintain its stability and efficacy. Understanding these handling requirements is crucial for laboratory and production personnel.

Conclusion

3,4-Dimethoxyphenylacetonitrile (CAS 93-17-4) is a cornerstone intermediate in the pharmaceutical and fine chemical industries. Its well-defined properties, critical applications, and the availability from efficient manufacturers make it a compound of significant interest. Whether you are a researcher seeking a building block or a procurement manager ensuring supply chain stability, understanding the facets of this chemical intermediate is key to successful sourcing and application.