Pentafluoroaniline in Pharmaceutical Synthesis: A Key Intermediate
The pharmaceutical industry's relentless pursuit of innovative and effective therapeutics hinges on the availability of high-quality chemical intermediates. Among these essential compounds, 2,3,4,5,6-Pentafluoroaniline, identified by CAS number 771-60-8, has emerged as a compound of significant interest. Its unique structural features and high purity make it an indispensable building block in the synthesis of a variety of advanced pharmaceutical agents. As a leading manufacturer and supplier, understanding and providing this crucial intermediate is central to our operations.
Pentafluoroaniline, with its molecular formula C6H2F5N and a molecular weight of approximately 183.08 g/mol, possesses a distinct advantage due to its highly fluorinated aromatic ring. The incorporation of fluorine atoms into drug molecules is a common strategy in medicinal chemistry. This strategy can enhance metabolic stability, increase lipophilicity (which aids in crossing cell membranes), and modulate the binding affinity of a drug to its target receptor. Consequently, 2,3,4,5,6-Pentafluoroaniline serves as a valuable scaffold for designing novel drug candidates with improved pharmacokinetic and pharmacodynamic profiles. The typical purity of ≥99.0% ensures that these beneficial effects can be reliably achieved in the final drug product.
The synthesis of complex active pharmaceutical ingredients (APIs) often requires specialized intermediates that offer specific reactivity and structural motifs. 2,3,4,5,6-Pentafluoroaniline fits this description perfectly, providing a reactive amino group attached to a stable, electron-deficient pentafluorophenyl ring. This structure allows for a wide range of synthetic transformations, enabling medicinal chemists to build intricate molecular architectures. For R&D departments and procurement managers, sourcing this intermediate from a reputable manufacturer is paramount to ensure the success of their drug development programs. Our role as a supplier is to provide this critical component with guaranteed quality and consistent availability.
The physical properties of Pentafluoroaniline, such as its melting point of 33-35°C and boiling point of 153°C, are also noteworthy. These characteristics contribute to its ease of handling and integration into standard chemical synthesis protocols. When considering purchasing 2,3,4,5,6-Pentafluoroaniline, it is essential to work with a supplier that can provide comprehensive technical data and assurance of product integrity. Our manufacturing processes are designed to meet the stringent requirements of the pharmaceutical industry, ensuring that every batch adheres to the highest standards.
For any pharmaceutical company engaged in research and development or scaling up production, securing a reliable supply of 2,3,4,5,6-Pentafluoroaniline is a strategic necessity. We invite research scientists and procurement specialists to connect with us for quotations and detailed product information. By partnering directly with a dedicated manufacturer, you can ensure the quality, consistency, and timely delivery of this vital pharmaceutical intermediate, thereby accelerating your journey from discovery to market.
Perspectives & Insights
Bio Analyst 88
“For R&D departments and procurement managers, sourcing this intermediate from a reputable manufacturer is paramount to ensure the success of their drug development programs.”
Nano Seeker Pro
“Our role as a supplier is to provide this critical component with guaranteed quality and consistent availability.”
Data Reader 7
“The physical properties of Pentafluoroaniline, such as its melting point of 33-35°C and boiling point of 153°C, are also noteworthy.”