The synthesis of peptides, whether for therapeutic, diagnostic, or research purposes, demands precision, efficiency, and the use of high-quality reagents. 1-[2-(Trimethylsilyl)ethoxycarbonyloxy]benzotriazole (Teoc-OBt) has carved out a significant niche in this field as a reagent for introducing the Teoc protecting group. This article explores the benefits of Teoc-OBt in peptide synthesis and highlights the advantages of sourcing this critical chemical intermediate from a reputable manufacturer and supplier.

Teoc-OBt, a white crystalline solid with a CAS number of 113306-55-1, plays a crucial role in preparing protected amino acids. These protected amino acids, such as Teoc-amino acids, are the fundamental building blocks used in constructing peptide chains. The Teoc group offers distinct advantages, primarily its orthogonal nature relative to other common protecting groups used in peptide synthesis. This means that the Teoc group can be removed selectively under specific conditions without disturbing other protective functionalities on the molecule. This selective deprotection is invaluable for complex peptide sequences and for minimizing side reactions, thereby improving the overall purity and yield of the target peptide.

While Teoc-OBt is highly effective, scientific literature points to the importance of purity and reaction optimization. For instance, trace amounts of dipeptide byproducts might form in specific synthetic contexts, emphasizing the need to procure Teoc-OBt from suppliers who guarantee high purity, typically 98% or above. When researchers and procurement managers decide to buy Teoc-OBt, they are essentially investing in the success of their peptide synthesis projects. Ensuring a reliable supply chain from a trusted manufacturer is therefore paramount.

As a leading chemical manufacturer and supplier in China, our company is committed to providing the scientific community with high-performance chemical intermediates like Teoc-OBt. We understand the critical requirements of peptide synthesis and ensure our product meets stringent purity specifications. By working directly with us, our clients gain access to competitive manufacturer pricing, making high-quality Teoc-OBt more accessible for both laboratory research and commercial production. We pride ourselves on being a dependable source for essential chemical building blocks, supporting innovation and efficiency in peptide synthesis and beyond. To obtain pricing and discuss your needs, we encourage you to request a quote from our sales team.