The pharmaceutical industry relies heavily on a diverse array of complex chemical intermediates to synthesize active pharmaceutical ingredients (APIs) and novel drug candidates. The precise molecular structure and high purity of these intermediates are paramount for ensuring drug efficacy and safety. One such vital compound gaining recognition for its synthetic utility is 1,4-dibromo-2,3-difluoro-5,6-dinitrobenzene (CAS: 1283598-32-2).

Chemical Profile and Significance

1,4-Dibromo-2,3-difluoro-5,6-dinitrobenzene, with its molecular formula C6Br2F2N2O4 and molecular weight of 361.88000, is a highly functionalized aromatic molecule. Its structure features bromine atoms and nitro groups on a difluorinated benzene ring, making it exceptionally reactive, particularly in nucleophilic aromatic substitution reactions. This reactivity profile positions it as a valuable building block for creating complex heterocyclic systems and introducing specific functionalities required in many pharmaceutical syntheses. Its melting point is 121.2°C, and its predicted boiling point is 321.4±37.0 °C, indicating it is a stable solid suitable for a wide range of chemical processes.

Applications in Pharmaceutical R&D and Manufacturing

The utility of 1,4-dibromo-2,3-difluoro-5,6-dinitrobenzene extends across several critical areas within pharmaceutical development:

  • API Synthesis: This intermediate can be a key component in the multi-step synthesis of various APIs, where precise functionalization is required. Its bromine atoms can serve as leaving groups or sites for cross-coupling reactions, while the nitro groups can be reduced to amines, opening pathways to diverse chemical structures.
  • Drug Discovery: In the early stages of drug discovery, researchers often require novel scaffolds and building blocks to explore new chemical space. This compound provides a versatile platform for generating libraries of potential drug candidates.
  • Process Development: For pharmaceutical companies scaling up production, securing a consistent supply of high-purity intermediates is essential. Understanding the chemical behavior and optimal reaction conditions for this compound is vital for efficient process development.

Strategic Sourcing for Pharmaceutical Needs

When you need to buy pharmaceutical intermediates like 1,4-dibromo-2,3-difluoro-5,6-dinitrobenzene, selecting a reliable manufacturer is critical. NINGBO INNO PHARMCHEM CO.,LTD. is a leading supplier in China that specializes in high-quality chemical intermediates. We offer this compound with a guaranteed purity of 97% minimum, ensuring it meets the stringent demands of pharmaceutical applications. We provide competitive prices and are ready to assist with your sourcing requirements. Contact us today to inquire about purchasing this essential intermediate and to request a sample, thereby ensuring the quality and continuity of your pharmaceutical R&D and manufacturing processes.