Phenylhydrazine (CAS 100-63-0) is a chemical compound widely utilized across various industries, most notably in the synthesis of pharmaceuticals, dyes, and agrochemicals. While its chemical versatility is highly valued, understanding its properties and implementing safe handling practices is paramount for all users. As a significant Phenylhydrazine manufacturer China, we emphasize the importance of knowledge regarding this compound.

Physical and Chemical Properties:

Phenylhydrazine typically appears as a colorless to pale yellow oily liquid. However, depending on purity and storage conditions, it can also exist as crystals. Purity grades commonly available include 92%, 95%, and 99%. Its molecular formula is C6H8N2, with a molecular weight of approximately 108.14 g/mol. Phenylhydrazine is known to be sparingly soluble in water but readily dissolves in organic solvents like ethanol, ether, chloroform, and benzene. Importantly, it is sensitive to air and light, which can cause it to darken over time, turning from yellow to reddish-brown.

Applications and Reactivity:

The primary utility of Phenylhydrazine lies in its role as a chemical intermediate. It is crucial for synthesizing pharmaceuticals such as Antipyrine, dyes like AS-G, and agrochemicals, including intermediates for pesticides and fungicides. Its reactivity also makes it a valuable reagent for identifying carbonyl groups in aldehydes and ketones and for facilitating complex organic reactions like the Fischer indole synthesis. When you look to buy Phenylhydrazine, understanding these applications helps in selecting the appropriate grade.

Safety and Handling Precautions:

Phenylhydrazine is classified as a hazardous substance and requires careful handling. It is toxic if swallowed, inhaled, or absorbed through the skin, and can cause skin and eye irritation. Prolonged or repeated exposure may lead to systemic effects such as anemia, jaundice, and damage to the liver and kidneys. Furthermore, Phenylhydrazine is considered a suspected mutagen and carcinogen. Therefore, stringent safety measures must be employed:

  • Personal Protective Equipment (PPE): Always wear appropriate PPE, including chemical-resistant gloves, safety goggles or a face shield, and protective clothing. Work in a well-ventilated area, preferably under a fume hood.
  • Storage: Store Phenylhydrazine in tightly sealed containers in a cool, dry, well-ventilated place, away from incompatible materials such as strong oxidizing agents, acids, and sources of ignition. Protect from light and air.
  • Handling: Avoid direct contact with skin, eyes, and clothing. Do not inhale vapors or mist. Ensure adequate ventilation. Keep containers tightly closed when not in use.
  • Spill Management: In case of spills, contain the material and absorb it with an inert material. Dispose of contaminated waste according to local regulations.

For businesses seeking to purchase Phenylhydrazine, it is essential to obtain comprehensive safety data sheets (SDS) from the supplier. A reliable supplier will not only provide quality product at a competitive Phenylhydrazine price but also offer crucial safety information. Ensuring proper training for personnel handling Phenylhydrazine is also a critical step in maintaining a safe working environment.

In summary, Phenylhydrazine (CAS 100-63-0) is a potent chemical intermediate whose safe and effective use relies on a thorough understanding of its properties and hazards. By adhering to strict safety protocols and sourcing from reputable manufacturers, industries can harness its chemical potential responsibly.