For procurement managers and R&D scientists in the chemical and pharmaceutical industries, understanding the intricate details of essential raw materials is critical. Povidone Iodine (PVP-I), a compound with CAS number 25655-41-8, stands out due to its potent antimicrobial efficacy and broad application range. This guide focuses on its key properties and offers insights for bulk buyers seeking to secure a reliable supply from a trusted Povidone Iodine manufacturer.

Key Properties of Povidone Iodine:

  • Chemical Composition: Povidone Iodine is a complex of polyvinylpyrrolidone (PVP) and iodine. The compound typically exhibits a concentration of 9.0-12.0% available iodine.
  • Physical Appearance: It is commonly supplied as a free-flowing, red-brown powder.
  • Solubility: PVP-I demonstrates excellent solubility in water and ethanol, facilitating its incorporation into various liquid formulations.
  • Antimicrobial Spectrum: Its broad-spectrum activity includes effectiveness against bacteria (Gram-positive and Gram-negative), viruses, fungi, and protozoa. This is attributed to the iodine component, which denatures microbial proteins.
  • Stability and Safety: Compared to elemental iodine, PVP-I is more stable, less irritating, and less toxic, making it a safer option for topical applications and general disinfection.

Quality Parameters for Bulk Procurement:

When sourcing PVP-I in bulk, several quality parameters should be rigorously evaluated to ensure suitability for your intended applications:

  1. Grade Compliance: Confirm that the product meets relevant pharmacopoeia standards such as USP (United States Pharmacopeia), BP (British Pharmacopoeia), or EP (European Pharmacopoeia) if intended for pharmaceutical or medical use.
  2. Purity and Assay: Verify the purity of the PVP-I and the consistent percentage of available iodine. Parameters like Loss on Drying, Residue on Ignition, and Heavy Metal content are also critical indicators of quality.
  3. Certifications: Request documentation like ISO, DMF, or GMP certifications from the manufacturer to ensure consistent quality and regulatory compliance.
  4. Packaging and Storage: Proper packaging (e.g., fiber drums) and recommended storage conditions (dry, cool, and air-tight) are essential for maintaining product integrity.

Sourcing Strategy for Bulk Buyers:

To secure a consistent and cost-effective supply of Povidone Iodine, consider the following:

  • Identify Reputable Manufacturers: Partner with established manufacturers who have a proven track record in producing high-quality PVP-I. Look for those with strong R&D capabilities and robust quality control systems.
  • Request Quotes and Samples: Obtain detailed quotes that include product specifications, pricing, and lead times. Always request samples for internal testing to validate performance and compatibility.
  • Negotiate Terms: Discuss payment terms, shipping options (e.g., FOB, CIF), and Incoterms. A reliable PVP Iodine supplier will offer transparent and favorable terms.
  • Build a Partnership: Establishing a long-term relationship with a trusted supplier can lead to better pricing, priority service, and improved supply chain security.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to being your preferred Povidone Iodine supplier. We offer high-quality PVP-I that meets rigorous standards, competitive PVP Iodine pricing, and exceptional service. Contact us to learn more about our bulk offerings and how we can support your business needs.