The development of stable and effective injectable drug formulations presents unique challenges, primarily concerning the solubility and stability of active pharmaceutical ingredients (APIs). Povidone (PVP), particularly its lower molecular weight grades such as Povidone K15 and Povidone K17, offers significant advantages as a cosolvent and dispersant. These grades are crucial for enhancing the performance of intravenous, intramuscular, and subcutaneous drug delivery systems. For pharmaceutical companies seeking a reliable PVP manufacturer in China for these specialized grades, NINGBO INNO PHARMCHEM CO.,LTD. is a premier choice.

Povidone (PVP) K15 and K17: Enhancing Injectable Formulations

Povidone (PVP), with its water-soluble polymer structure (CAS 9003-39-8), exhibits excellent complexation capabilities. When used as a cosolvent or dispersant in injectable formulations, PVP K15 and K17 function by:

  • Increasing API Solubility: They form complexes with poorly soluble APIs, effectively increasing their concentration in aqueous solutions and enabling the preparation of clear, stable injectable products. This is vital for achieving therapeutic drug concentrations.
  • Stabilizing Dispersions: For APIs that are formulated as suspensions, PVP acts as a steric stabilizer, preventing particle aggregation and ensuring a uniform distribution of the drug. This maintains the efficacy and safety of the formulation over its shelf life.
  • Inhibiting Crystallization: PVP can prevent the crystallization or precipitation of APIs during storage, which is a common issue for solutions that may be stored for extended periods or exposed to temperature fluctuations.
  • Improving Drug Delivery: By ensuring better solubility and dispersion, PVP contributes to more consistent and predictable drug release and absorption after administration.

Key Applications for Povidone K15 and K17

These specific grades of Povidone find application in a wide array of injectable products. Examples include:

  • Solubilization of antibiotics and other APIs.
  • Stabilization of protein-based therapeutics.
  • Enhancing the delivery of poorly soluble drugs in specialized formulations.

When you buy Povidone K15 for injections or seek Povidone K17, you are looking for a product that meets stringent pharmaceutical quality requirements.

Your Trusted Partner for Pharmaceutical Grade PVP

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying high-purity Povidone (PVP) that meets the rigorous demands of the pharmaceutical industry. Our Povidone K15 and K17 grades are manufactured to exacting standards, ensuring >96% purity and compliance with international pharmacopoeias, supported by certifications like GMP, ISO 9001, and CEP. As a leading PVP supplier in China, we offer stable quantities and competitive pricing, making us an ideal partner for your procurement needs. We are committed to helping you purchase high-purity PVP with confidence.

Secure the quality and performance of your injectable formulations by choosing NINGBO INNO PHARMCHEM CO.,LTD. for your Povidone (PVP) K15 and K17 requirements. Contact us today to discuss your specific needs and receive a competitive quote.