In the dynamic fields of neuroscience, pharmacology, and biochemistry, the availability of high-quality research reagents is non-negotiable. 2-Arachidonoylglycerol (2-AG), a critical endocannabinoid and potent agonist for cannabinoid receptors, is one such compound that researchers frequently require. Ensuring a reliable supply chain for this molecule is essential for the continuity and validity of scientific investigations.

The Scientific Significance of 2-Arachidonoylglycerol

2-AG, with its CAS number 53847-30-6, is a naturally occurring lipid that plays a crucial role in the endocannabinoid system (ECS). Its primary function is to activate CB1 and CB2 receptors, which are involved in regulating a multitude of physiological processes, including pain modulation, appetite control, immune function, and neuroprotection. As a full agonist, 2-AG elicits a strong biological response, making it a vital tool for studying receptor pharmacology and developing potential therapeutic interventions. Researchers looking to buy 2-AG are often investigating its role in neurological disorders, inflammation, and metabolic diseases.

Factors Influencing 2-AG Price and Availability

The price of 2-Arachidonoylglycerol can vary significantly based on several factors. Firstly, purity is a major determinant; higher purity grades (e.g., ≥95%) command higher prices due to the rigorous purification processes involved. Secondly, the scale of purchase influences cost; bulk orders from manufacturers typically offer a lower price per gram compared to smaller research quantities. Thirdly, the reputation and quality control standards of the manufacturer or supplier play a role. A supplier with robust quality assurance, evidenced by detailed Certificates of Analysis (CoA), may charge more but provides greater confidence in the product's integrity.

Why Partner with a Trusted Supplier?

When it comes to specialized biochemicals like 2-AG, the reliability of the supplier is paramount. A trusted supplier ensures:

  • Consistent Quality: Batches of 2-AG meet the specified purity and compositional standards.
  • Timely Delivery: Research projects often have strict timelines, making prompt delivery crucial.
  • Technical Support: Access to experts who can answer questions about product specifications, handling, and storage.
  • Secure Supply Chain: Assurance that the product will be available when needed, minimizing disruptions to research.

Many researchers turn to established manufacturers and suppliers in regions like China, known for their advanced chemical synthesis capabilities. These suppliers can often provide 2-AG at competitive prices while maintaining high-quality standards. When considering a purchase, it's advisable to request detailed product information and inquire about any available discounts for bulk orders.

In conclusion, securing a reliable supply of high-purity 2-Arachidonoylglycerol is foundational for advancing research in the endocannabinoid system. By understanding the scientific importance of 2-AG and carefully selecting a reputable manufacturer and supplier, researchers can ensure the integrity and success of their investigations.