For procurement managers in the pharmaceutical sector, sourcing critical intermediates like 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine (CAS 1180132-17-5) requires a systematic approach. This compound is a key intermediate in the synthesis of Abemaciclib, an important oncology drug. Ensuring a reliable supply of high-quality material is paramount to maintaining production schedules and drug efficacy.

When you are tasked to buy this vital Abemaciclib intermediate, consider the following checklist:

  • Purity and Specifications: Verify that the supplier can consistently provide 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine with the required purity levels (e.g., >98%). Request detailed Certificates of Analysis (CoA) for each batch, including results from HPLC, GC-MS, and NMR.
  • Supplier Reliability and Reputation: Look for manufacturers with a proven track record in producing pharmaceutical intermediates. A supplier based in China, such as our company, can offer competitive advantages, but due diligence is essential. Check for certifications (e.g., ISO) and customer testimonials.
  • Manufacturing Capabilities: Assess the supplier's production capacity and scalability. Can they meet your projected demand, from R&D quantities to bulk manufacturing? Understanding their synthesis process and quality control measures is important.
  • Regulatory Compliance: Ensure the manufacturer adheres to relevant industry standards and can provide necessary documentation for regulatory submissions if required.
  • Pricing and Lead Times: Obtain clear pricing for your required quantities and understand the lead times for delivery. Competitive pricing from a Chinese manufacturer can be a significant benefit.

As a leading manufacturer and supplier of pharmaceutical intermediates in China, we are committed to meeting these criteria. We understand the critical nature of compounds like CAS 1180132-17-5 for the development of essential medicines like Abemaciclib. We encourage procurement professionals to engage with us to secure a dependable and high-quality source for your intermediate needs.