Procurement Guide: Buying 2-Chloro-1-(3,4-difluorophenyl)ethanone for API Synthesis
For procurement professionals and R&D scientists in the pharmaceutical sector, sourcing high-quality chemical intermediates is a daily challenge. Among these critical materials is 2-chloro-1-(3,4-difluorophenyl)ethanone (CAS: 51336-95-9), a vital component in the synthesis of the widely used antiplatelet drug, Ticagrelor. This guide aims to provide clarity on what to look for when you decide to buy this essential intermediate, focusing on quality, supplier credibility, and application requirements.
Understanding the Core Specifications
When procuring 2-chloro-1-(3,4-difluorophenyl)ethanone, the most critical specification is purity. As a key intermediate for an API, an assay of ≥98.0% is typically the benchmark. This ensures minimal impurities, which can lead to adverse effects in the final drug product or complicated purification processes. Beyond the assay, understanding physical properties like appearance (white to light yellow crystal), density, boiling point, and flash point is crucial for safe handling, storage, and integration into existing synthetic protocols. Always request a detailed Certificate of Analysis (CoA) from your supplier.
Selecting a Credible Manufacturer and Supplier
The reliability of your supply chain hinges on the credibility of your chemical manufacturer and supplier. For 2-chloro-1-(3,4-difluorophenyl)ethanone, consider manufacturers with a proven track record in producing fine chemicals and pharmaceutical intermediates. Key indicators of credibility include adherence to international quality standards, robust manufacturing capacity, transparent communication, and a history of consistent delivery. As a manufacturer based in China, we pride ourselves on meeting these criteria, offering both high-quality products and dependable service.
The Importance for Ticagrelor Synthesis
The demand for 2-chloro-1-(3,4-difluorophenyl)ethanone is directly linked to the therapeutic importance of Ticagrelor. Ticagrelor is prescribed to reduce the risk of thrombotic events in patients with acute coronary syndromes. The efficient and effective synthesis of this API relies heavily on the quality and availability of its precursors. Therefore, when you buy this intermediate, you are contributing to the production of a medication that impacts millions of lives globally. Choosing a supplier that understands the critical nature of these applications is paramount.
Logistics, Packaging, and Purchase Considerations
Logistics and packaging are also important factors. Standard packaging, such as 25 kg drums, is common, but inquire about custom packaging options to suit your facility's needs and handling capabilities. Lead times for international shipments from China can vary, so planning your procurement well in advance is advisable. We offer flexible packaging and work with clients to optimize delivery schedules for their purchases of 2-chloro-1-(3,4-difluorophenyl)ethanone.
For companies looking to buy 2-chloro-1-(3,4-difluorophenyl)ethanone, partnering with a reputable Chinese manufacturer like us ensures quality, competitive pricing, and supply chain stability. We invite you to contact us to discuss your specific requirements and experience the benefits of our reliable service.
Perspectives & Insights
Chem Catalyst Pro
“The Importance for Ticagrelor SynthesisThe demand for 2-chloro-1-(3,4-difluorophenyl)ethanone is directly linked to the therapeutic importance of Ticagrelor.”
Agile Thinker 7
“Ticagrelor is prescribed to reduce the risk of thrombotic events in patients with acute coronary syndromes.”
Logic Spark 24
“The efficient and effective synthesis of this API relies heavily on the quality and availability of its precursors.”