Understanding Fmoc-Lys(Boc)-OH: A Procurement Guide for Peptide Synthesis Materials
For procurement professionals in the pharmaceutical, biotechnology, and academic research sectors, sourcing high-quality raw materials is a critical aspect of ensuring project success. Fmoc-Lys(Boc)-OH is a specialized amino acid derivative essential for solid-phase peptide synthesis (SPPS), a technique widely employed for creating custom peptides. This guide aims to provide procurement managers with a clear understanding of Fmoc-Lys(Boc)-OH, its importance, and how to source it effectively from reliable manufacturers like NINGBO INNO PHARMCHEM CO.,LTD.
Fmoc-Lys(Boc)-OH (CAS 71989-26-9) is a derivative of the natural amino acid lysine, modified with two protecting groups: the Fmoc (9-fluorenylmethyloxycarbonyl) group attached to the alpha-amino group and the Boc (tert-butyloxycarbonyl) group attached to the epsilon-amino group of the lysine side chain. The Fmoc group serves as a temporary protecting group that is removed by a mild base (e.g., piperidine), allowing the alpha-amino group to react with the activated carboxyl group of the next incoming amino acid. The Boc group on the lysine side chain is stable under these basic conditions but is readily cleaved by a moderate acid (e.g., trifluoroacetic acid) during the final deprotection step. This orthogonal protection scheme is fundamental to achieving efficient and specific peptide bond formation.
When evaluating suppliers, procurement managers should prioritize consistency in purity, reliable delivery, and competitive pricing. NINGBO INNO PHARMCHEM CO.,LTD. is a leading Fmoc-Lys(Boc)-OH supplier known for its commitment to quality. We ensure our Fmoc-Lys(Boc)-OH typically exceeds 99% purity, which is vital for minimizing side reactions and ensuring the integrity of synthesized peptides. Understanding the Fmoc-Lys(Boc)-OH price in relation to quality is essential; investing in high-purity material from a trusted Fmoc-Lys(Boc)-OH manufacturer often proves more cost-effective in the long run by reducing downstream purification costs and synthesis failures.
The applications of Fmoc-Lys(Boc)-OH are extensive. It is used in the synthesis of therapeutic peptides, diagnostic markers, and peptides for cosmetic applications. Researchers also utilize it for creating peptide libraries, peptide probes for biological assays, and modified peptides with enhanced stability or targeting capabilities. For any procurement manager looking to purchase Fmoc-Lys(Boc)-OH, selecting a supplier with a proven track record, robust quality control, and responsive customer service is crucial. As a prominent manufacturer based in China, we are well-positioned to support global demands with efficient logistics and comprehensive product documentation.
In conclusion, Fmoc-Lys(Boc)-OH is a vital component in modern peptide synthesis. By focusing on purity, reliability, and the expertise of the supplier, procurement managers can ensure the success of their peptide synthesis projects. We invite you to contact NINGBO INNO PHARMCHEM CO.,LTD. for your Fmoc-Lys(Boc)-OH needs and to request a quotation for bulk purchases.
Perspectives & Insights
Bio Analyst 88
“, piperidine), allowing the alpha-amino group to react with the activated carboxyl group of the next incoming amino acid.”
Nano Seeker Pro
“The Boc group on the lysine side chain is stable under these basic conditions but is readily cleaved by a moderate acid (e.”
Data Reader 7
“This orthogonal protection scheme is fundamental to achieving efficient and specific peptide bond formation.”