In the intricate supply chains of the chemical and pharmaceutical industries, the procurement of critical intermediates is a strategic imperative. 2-(Chloromethyl)quinoline Hydrochloride (CAS 3747-74-8) stands as one such compound, prized for its role as a versatile building block in the synthesis of pharmaceuticals and other specialized chemicals. For procurement managers and R&D scientists, understanding how to effectively source this material is key to maintaining project timelines and ensuring product quality. This guide aims to shed light on the procurement aspects of 2-(Chloromethyl)quinoline Hydrochloride.

Understanding the Product: 2-(Chloromethyl)quinoline Hydrochloride

This compound is characterized by a quinoline heterocyclic structure with a reactive chloromethyl group at the 2-position. It is commonly supplied as a pale yellow to cream or light pink powder, typically with a minimum purity of 97%. The hydrochloride salt form enhances its stability and handling properties, making it suitable for industrial use. Its primary applications lie in its function as a pharmaceutical intermediate, where it serves as a crucial precursor for synthesizing various APIs. It is also utilized in the creation of fluorescent probes, highlighting its importance in both drug development and advanced research applications.

Key Considerations for Procurement: Quality and Purity

When looking to buy 2-(chloromethyl)quinoline hydrochloride, the paramount consideration for any buyer is quality, specifically purity. For pharmaceutical applications, even slight deviations in purity can lead to costly downstream issues or compromise the integrity of the final product. Therefore, it is essential to partner with a manufacturer that can consistently deliver material meeting high purity standards (e.g., >97%). Requesting and scrutinizing Certificates of Analysis (COA) for each batch is a standard practice. Additionally, understanding the safety profile through Material Safety Data Sheets (MSDS) is crucial for safe handling and storage.

Finding Reliable Suppliers and Manufacturers

The global chemical market offers numerous options for sourcing 2-(Chloromethyl)quinoline Hydrochloride. However, identifying a reliable supplier is critical. Many leading chemical manufacturers and distributors, particularly those based in China, specialize in producing and supplying pharmaceutical intermediates. These suppliers often offer competitive pricing, especially for bulk purchase orders, making them attractive partners for cost-conscious organizations. When evaluating potential suppliers, consider factors such as:

  • Production Capacity: Can they meet your volume requirements consistently?
  • Quality Control: Do they have robust QC processes and provide comprehensive documentation?
  • Lead Times: How quickly can they deliver, and what are their shipping capabilities?
  • Technical Support: Do they offer technical assistance or custom synthesis services if needed?
  • Sample Availability: Are free samples offered for initial quality assessment?

Inquiring about the cas 3747-74-8 price from several reputable sources will allow for effective price comparison and negotiation. Building a strong relationship with a trusted supplier can streamline future procurement processes and ensure a stable supply of this vital chemical intermediate.

Conclusion

2-(Chloromethyl)quinoline Hydrochloride is an indispensable component in modern chemical synthesis, particularly for the pharmaceutical industry. By understanding its properties, prioritizing quality and purity, and diligently selecting reliable manufacturers and suppliers, procurement professionals can ensure the seamless integration of this vital intermediate into their research and production workflows.