In the dynamic world of pharmaceutical procurement, staying informed about the market trends and reliable sourcing strategies for key intermediates is crucial. 2,5-Dichloro-N-(2-(isopropylsulfonyl)phenyl)pyrimidin-4-amine, identified by its CAS number 761440-16-8, is a critical compound for the synthesis of Ceritinib, a vital targeted therapy. This article provides procurement professionals with insights into effectively sourcing this important chemical.

The Strategic Importance of 761440-16-8

As a fundamental building block for Ceritinib, an ALK inhibitor used to treat specific forms of non-small cell lung cancer, the demand for 2,5-Dichloro-N-(2-(isopropylsulfonyl)phenyl)pyrimidin-4-amine is directly linked to the success of this therapeutic. The quality of this intermediate, characterized by its purity (typically ≥98.0%) and the absence of critical impurities, directly impacts the efficiency and output of the Ceritinib manufacturing process. High-purity intermediates lead to better yields and a more reliable final API.

Market Dynamics: Finding the Right Supplier

Procurement professionals tasked with securing this intermediate need to identify dependable suppliers. When you search to buy 2,5-Dichloro-N-(2-(isopropylsulfonyl)phenyl)pyrimidin-4-amine, consider the following criteria for evaluating potential partners:

  • Supplier Location and Capacity: China is a major hub for chemical manufacturing. Identifying a strong 2,5-Dichloro-N-(2-(isopropylsulfonyl)phenyl)pyrimidin-4-amine manufacturer in China can offer cost benefits and production scale.
  • Quality Documentation: Insist on comprehensive Certificates of Analysis (CoA) and understand the supplier's quality management systems.
  • Pricing and Negotiation: Obtain quotes from multiple suppliers to secure a competitive Ceritinib intermediate price. Understand the pricing structure for different quantities.
  • Logistics and Compliance: Ensure the supplier can manage international shipping regulations and provide necessary safety data sheets (SDS).

For specialized needs, exploring custom synthesis 761440-16-8 services from a proven provider might be necessary. A robust supply chain is built on strong relationships with trusted CAS 761440-16-8 suppliers.

Key Procurement Considerations

Beyond price, the long-term reliability of a supplier is paramount. Factors such as consistent product quality, on-time delivery, and responsive customer service contribute to a successful procurement strategy. Building strong relationships with key manufacturers ensures a stable supply of essential intermediates, supporting the continuous production of life-saving pharmaceuticals like Ceritinib.

Ultimately, the procurement of 2,5-Dichloro-N-(2-(isopropylsulfonyl)phenyl)pyrimidin-4-amine requires diligence, a focus on quality, and a strategic approach to supplier selection. By understanding market dynamics and prioritizing reliable partnerships, procurement professionals can ensure the efficient and effective sourcing of this critical chemical.