For B2B buyers in the pharmaceutical and fine chemical industries, the procurement of specialized intermediates like 11-Alpha-Hydroxycanrenone Methyl Ester (CAS 192704-56-6) demands a strategic approach. This compound is not merely a chemical; it's a critical link in the value chain for producing vital cardiovascular medications, most notably Eplerenone. Understanding its applications, quality requirements, and the best sourcing strategies is essential for ensuring supply chain continuity and product integrity.

The primary application driving the demand for 11-Alpha-Hydroxycanrenone Methyl Ester is its indispensable role as an intermediate in the synthesis of Eplerenone. This medication is widely prescribed for managing hypertension and post-myocardial infarction heart failure. Therefore, consistent access to high-purity 11-Alpha-Hydroxycanrenone Methyl Ester is a prerequisite for manufacturers of this API. Buyers are typically seeking a white to off-white solid with a guaranteed minimum purity, often exceeding 98% or 99%, to ensure the efficacy and safety of the final drug product.

When searching for manufacturers and suppliers, potential buyers will often look for comprehensive technical data. This includes detailed information on the molecular formula (C24H32O6), molecular weight (416.51), CAS number (192704-56-6), and potentially spectral data such as NMR, MS, and HPLC chromatograms. A reliable supplier, such as those found in China, will readily provide these documents along with a Certificate of Analysis (CoA) for each batch. This documentation is crucial for internal quality assurance and regulatory compliance.

For B2B procurement, understanding pricing structures is also key. While the initial inquiry might be for a price quote, buyers should be prepared to discuss quantity requirements. Manufacturers often offer tiered pricing, where the per-unit cost decreases significantly with larger order volumes. This makes it cost-effective for large-scale production needs. For R&D departments, smaller quantities are usually available, allowing for initial project feasibility studies without substantial upfront investment.

Navigating the global supply market, particularly when looking to buy from China, requires diligence. It's advisable to partner with suppliers who have a proven track record, clear communication channels, and robust quality management systems. Many Chinese manufacturers are highly experienced in international trade, offering various Incoterms (like FOB, CFR, EXW) and payment options (L/C, T/T, PayPal) to facilitate global transactions. Their ability to provide stable production capacity and timely delivery is a testament to their operational efficiency.

In summary, the procurement of 11-Alpha-Hydroxycanrenone Methyl Ester involves more than just identifying a supplier. It requires a thorough understanding of the product's critical role in Eplerenone synthesis, its quality specifications, and the nuances of sourcing from global manufacturers. By engaging with reputable China suppliers, B2B buyers can secure a reliable and cost-effective supply of this vital pharmaceutical intermediate, supporting the continued production of essential cardiovascular therapies.