For scientists and procurement specialists in the pharmaceutical and fine chemical industries, the ability to source high-quality raw materials is fundamental to success. 1,2,3,4,6-Penta-O-acetyl-alpha-D-galactopyranose (CAS 4163-59-1) is a prime example of such an essential compound. As an acetylated derivative of galactose, it serves as a critical intermediate in organic synthesis and pharmaceutical research. This guide aims to equip potential buyers with the knowledge needed to procure this valuable chemical effectively.

Understanding the Product: Specifications and Properties

1,2,3,4,6-Penta-O-acetyl-alpha-D-galactopyranose, with CAS number 4163-59-1, is typically supplied as a white powder. Its molecular formula is C16H22O11, and it has a molecular weight of approximately 390.12 g/mol. A key specification to look for when you buy this product is its purity, which is commonly stated as ≥98%. This high level of purity is vital for its applications, ensuring predictable outcomes in complex chemical reactions and the synthesis of high-quality pharmaceutical ingredients.

The acetyl groups attached to the hydroxyl positions of the galactose molecule serve as protective groups. This protection strategy is crucial for chemists, as it allows for controlled reactions at specific sites on the sugar molecule, particularly at the anomeric carbon. These protected sugars are thus key intermediates for creating more complex structures.

Key Applications and Their Impact on Demand

The demand for 1,2,3,4,6-Penta-O-acetyl-alpha-D-galactopyranose is largely driven by its utility in several critical areas:

  • Pharmaceutical Intermediates: It is widely used in the synthesis of various glycosides and carbohydrate-modified drug molecules. This includes developing novel antibiotics, antiviral agents, and cancer therapeutics where specific sugar moieties are essential for biological activity or drug delivery. Pharmaceutical companies often require this intermediate for API manufacturing.
  • Organic Synthesis: Beyond pharmaceuticals, this compound is a valuable building block in general organic synthesis for academic and industrial researchers. It allows for the construction of complex molecules and carbohydrate-based materials.
  • Cosmetics and Specialty Chemicals: While less common, derivatives of protected sugars can find their way into niche applications within the cosmetics and specialty chemical industries, leveraging their unique functional properties.

For procurement professionals, understanding these applications helps in determining the required quantity and quality specifications. When you decide to buy, consider your long-term needs to potentially benefit from bulk purchasing discounts.

Procurement Strategies: Finding Reliable Manufacturers and Suppliers

When looking to purchase 1,2,3,4,6-Penta-O-acetyl-alpha-D-galactopyranose, partnering with a reliable manufacturer is paramount. Key considerations include:

  • Reputation and Experience: Seek out manufacturers with a proven track record in producing fine chemicals and pharmaceutical intermediates. Companies with established export operations, particularly those based in China, often provide a good balance of quality and cost.
  • Quality Control: Insist on comprehensive Certificates of Analysis (CoAs) for each batch. These documents should detail purity levels and the analytical methods used (e.g., HPLC, NMR).
  • Pricing and Terms: Obtain quotes from several suppliers to compare pricing, minimum order quantities, and payment terms (e.g., T/T, L/C, Paypal). Negotiating favorable Incoterms (like FOB or CFR) can also impact overall cost and logistics.
  • Logistics and Delivery: Confirm shipping options (Air, Ocean, express courier services like DHL/TNT) and estimated lead times to ensure alignment with your project timelines. Major ports like Shanghai or Qingdao in China are common export points.

For instance, if you are seeking to buy this compound for your laboratory or manufacturing needs, engaging with a dedicated manufacturer in China can offer significant advantages in terms of both cost-effectiveness and supply reliability. Such suppliers often have the capacity to fulfill orders ranging from grams for research to kilograms or tons for commercial production.

Conclusion

1,2,3,4,6-Penta-O-acetyl-alpha-D-galactopyranose (CAS 4163-59-1) is a critical chemical intermediate with diverse applications, especially in the pharmaceutical and organic synthesis fields. By understanding its specifications, applications, and by partnering with experienced manufacturers and suppliers, buyers can ensure they procure this essential compound efficiently and cost-effectively. Prioritize quality and reliability to guarantee the integrity and success of your research and production processes.