For procurement managers in the pharmaceutical industry, sourcing critical intermediates like 3,5-Dimethyl-4-nitropyridine 1-Oxide (CAS: 14248-66-9) requires a meticulous approach. This compound is a cornerstone in the synthesis of widely used proton pump inhibitors (PPIs), making its consistent quality and availability paramount. Understanding the market and key supplier attributes can significantly streamline your purchasing process.

Understanding the Product: 3,5-Dimethyl-4-nitropyridine 1-Oxide

This chemical, often described as a bright yellow crystalline powder, is valued for its specific molecular structure and high purity, typically at or above 98%. Its primary application lies in its role as a key intermediate in the production of blockbuster drugs such as Omeprazole, Pantoprazole, and Rebeprazole. These medications are vital for treating gastrointestinal issues, and a stable supply of their intermediates is non-negotiable for manufacturers.

Key Considerations for Procurement:

  • Quality and Purity: Always prioritize suppliers who can guarantee a minimum purity of 98% and provide comprehensive Certificates of Analysis (CoA). For pharmaceutical applications, purity directly impacts the efficacy and safety of the final API. Low Loss on Drying (LOD) values are also indicative of a high-quality product.
  • Supplier Reliability: When you need to buy 3,5-Dimethyl-4-nitropyridine 1-Oxide, look for established manufacturers and suppliers with a proven track record. Companies that offer transparent documentation, robust quality control, and reliable delivery schedules are preferred. Especially when sourcing from China, partnering with reputable firms ensures adherence to international standards.
  • Pricing and Cost-Effectiveness: While quality is paramount, competitive pricing is a significant factor for procurement managers. Understanding the market price for 3,5-Dimethyl-4-nitropyridine 1-Oxide from various manufacturers in China can help in securing cost-effective solutions without compromising on quality. Requesting quotes from multiple suppliers is a standard practice.
  • Supply Chain Stability: Given the consistent global demand for PPIs, ensuring a stable supply chain for intermediates like 4-nitro-3,5-dimethylpyridine N-oxide is crucial. Look for suppliers who can demonstrate scalability and have contingency plans to manage potential disruptions.
  • Regulatory Compliance: Ensure your chosen supplier can provide necessary regulatory documentation, such as DMF (Drug Master File) support, if required for your specific market. This is especially important for products intended for pharmaceutical use.

Why Choose a Specialized Manufacturer?

As NINGBO INNO PHARMCHEM CO.,LTD., we specialize in providing high-quality pharmaceutical intermediates. Our manufacturing capabilities in China are optimized for precision and efficiency, allowing us to offer 3,5-Dimethyl-4-nitropyridine 1-Oxide at competitive prices while maintaining stringent quality standards. We understand the critical nature of these compounds for API synthesis and are dedicated to being a reliable partner for your procurement needs. For those looking to purchase this essential chemical, engaging with a seasoned manufacturer like us ensures you receive not just a product, but a reliable component of your manufacturing success.