For professionals in the chemical and pharmaceutical industries, the procurement of specialized intermediates like 3-Chloro-5-hydroxybenzonitrile (CAS 473923-97-6) is a critical process that directly impacts research outcomes and production efficiency. This compound serves as a foundational element in many synthesis pathways, making its reliable acquisition a priority for many organizations.

The Role of 3-Chloro-5-hydroxybenzonitrile in Synthesis

3-Chloro-5-hydroxybenzonitrile is a key intermediate primarily recognized for its utility in organic synthesis, particularly within the pharmaceutical domain. Its chemical structure, a chlorinated benzonitrile with a hydroxyl group, allows for a range of chemical reactions, including the formation of heterocyclic compounds and complex molecular frameworks. A notable application is its use in the synthesis of Doravirine, an important antiretroviral drug. This critical role highlights why many R&D scientists and process chemists look to buy this specific intermediate for their development projects, aiming to create advanced APIs and other fine chemicals.

Key Procurement Factors for Buyers

When purchasing 3-Chloro-5-hydroxybenzonitrile, B2B buyers typically focus on several key attributes to ensure the material meets their stringent requirements. These include:

  • Purity and Assay: High purity is essential for pharmaceutical intermediates. A typical specification is an assay of ≥98.0%, often verified by GC analysis.
  • Physical Form: The compound is usually supplied as a white to almost white powder or crystalline solid, facilitating ease of handling.
  • CAS Number: 473923-97-6 is the definitive identifier for this chemical, ensuring accurate sourcing.
  • Supplier Reliability: Partnering with manufacturers known for consistent quality and stable supply chains is paramount.
  • Pricing and Packaging: Competitive pricing and appropriate packaging (e.g., 25 kg drums) are important for cost management and production scale.

Navigating the Supplier Landscape

The global chemical market offers numerous suppliers for 3-Chloro-5-hydroxybenzonitrile, with a significant number of manufacturers located in China. Companies like NINGBO INNO PHARMCHEM CO.,LTD. are established players, providing direct access to this intermediate. When you aim to buy this chemical, comparing quotes from multiple reputable manufacturers is advisable. Factors such as manufacturing scale, quality control processes, and adherence to regulatory standards should be evaluated to ensure a secure and high-quality supply for your organization.

Why Partner with NINGBO INNO PHARMCHEM CO.,LTD.?

At NINGBO INNO PHARMCHEM CO.,LTD., we pride ourselves on being a premier manufacturer and supplier of essential chemical intermediates. Our commitment to quality, backed by rigorous production standards and comprehensive quality assurance, makes us an ideal partner for your procurement needs. We understand the critical importance of intermediates like 3-Chloro-5-hydroxybenzonitrile in driving innovation in the pharmaceutical and fine chemical industries. By choosing us, you gain a reliable source committed to providing exceptional value and consistent supply.

In summary, the strategic procurement of 3-Chloro-5-hydroxybenzonitrile is fundamental for successful R&D and manufacturing. By focusing on purity, supplier reliability, and competitive pricing, buyers can secure the essential building blocks needed to advance their projects and bring innovative solutions to market.