For professionals in the pharmaceutical and agrochemical industries, securing reliable sources for key intermediates is paramount. 4-Bromo-1H-pyrrolo[2,3-c]pyridine, identified by CAS number 69872-17-9, stands out as a crucial building block in the synthesis of a wide array of biologically active compounds. Understanding how to procure this fine chemical intermediate efficiently is vital for research and development teams aiming to innovate and optimize their production pipelines. This guide is tailored for procurement managers and R&D scientists looking to source this compound, focusing on the benefits of partnering with manufacturers and suppliers in China.

Understanding 4-Bromo-1H-pyrrolo[2,3-c]pyridine's Value Proposition

4-Bromo-1H-pyrrolo[2,3-c]pyridine, also known by synonyms such as 4-Bromo-6-azaindole, is a heterocyclic compound with a unique structure that lends itself to diverse chemical transformations. Its primary utility lies in its role as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The bromine atom at the 4-position is particularly reactive, making it an excellent handle for palladium-catalyzed cross-coupling reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations. These reactions allow chemists to introduce various functional groups, paving the way for the creation of complex molecules with targeted biological activities. For example, derivatives of this scaffold have shown promise in developing anticancer agents, antiviral compounds, and molecules targeting inflammatory pathways. Research into its applications also highlights its potential in addressing challenges like drug resistance and identifying novel therapeutic targets.

Key Considerations for Buyers: Quality and Purity

When sourcing chemical intermediates, the purity of the product is non-negotiable. Impurities can significantly impact reaction yields, product quality, and the overall cost-effectiveness of a synthesis. Therefore, it is crucial to partner with manufacturers who can guarantee high purity levels for 4-Bromo-1H-pyrrolo[2,3-c]pyridine. Reputable suppliers will provide detailed certificates of analysis (CoA) that include spectroscopic data such as NMR, HPLC, and GC-MS, confirming the identity and purity of the material. As a potential buyer, you should look for suppliers who clearly state their quality control measures and manufacturing standards. The appearance of the compound, typically a white to light brown solid, should also align with specifications. Understanding the typical physical and chemical properties, such as melting point (around 188-189°C) and solubility characteristics, can further aid in quality assessment.

Navigating the Sourcing Process: Manufacturers and Suppliers in China

China has emerged as a global hub for the production and supply of fine chemicals and intermediates. When looking to buy 4-Bromo-1H-pyrrolo[2,3-c]pyridine, partnering with a Chinese manufacturer or supplier offers several advantages, including competitive pricing, large-scale production capabilities, and access to a wide range of chemical expertise. For companies seeking to purchase this compound, it is advisable to engage with established chemical companies that have a proven track record in the industry. These suppliers often specialize in custom synthesis and bulk orders, catering to the specific needs of R&D departments and large-scale manufacturers.

When evaluating potential suppliers, consider factors beyond just price. Look for companies that offer responsive customer service, reliable logistics, and transparent communication. The ability to request samples for initial testing is also a critical step in the procurement process. Engaging with a trusted manufacturer ensures a stable supply chain, which is essential for uninterrupted research and production schedules. Furthermore, understanding the Incoterms (e.g., FOB, CIF) and payment terms (T/T, L/C) is crucial for a smooth transaction. As a reliable manufacturer and supplier, we are committed to providing high-quality 4-Bromo-1H-pyrrolo[2,3-c]pyridine, ensuring that your procurement process is efficient and your projects benefit from consistent, high-purity intermediates. We welcome your inquiries for bulk purchases and can provide comprehensive technical support to facilitate your synthesis goals.