For procurement professionals in the chemical and pharmaceutical industries, identifying reliable sources for critical raw materials is a continuous challenge. 5-Acetylsalicylamide, with its CAS number 40187-51-7, is one such intermediate that plays a significant role, particularly in the synthesis of pharmaceutical agents like Labetalol. This article aims to guide buyers on how to effectively source this compound, focusing on quality, applications, and the benefits of partnering with trusted manufacturers and suppliers.

What is 5-Acetylsalicylamide?

5-Acetylsalicylamide is an organic chemical compound with the molecular formula C9H9NO3. It is recognized for its use as a pharmaceutical intermediate. Its physical characteristics include an off-white to light yellow crystalline powder appearance, with a melting point typically around 220-222 °C. Its density is noted at 1.297 g/cm³. These specifications are crucial for quality control and application suitability. As a supplier, NINGBO INNO PHARMCHEM CO.,LTD. provides detailed information on these properties to assist buyers in their decision-making process.

Key Applications in Pharmaceutical Synthesis

The primary noted application for 5-Acetylsalicylamide is its role as a crucial intermediate in the synthesis of Labetalol. Labetalol is a vital medication used for managing hypertension. The purity and consistent quality of 5-Acetylsalicylamide directly impact the yield and purity of the final Labetalol API. Therefore, it is imperative for pharmaceutical companies to buy this intermediate from manufacturers with robust quality assurance systems. For R&D scientists, this compound can also serve as a building block for other synthetic pathways, making it a versatile material in organic chemistry.

Choosing a Reliable Manufacturer and Supplier

When seeking to purchase 5-Acetylsalicylamide, buyers should look for manufacturers that can guarantee high purity (typically ≥98.0%) and offer consistent quality across batches. A reliable manufacturer in China will have stringent quality control processes, provide necessary technical data sheets (TDS) and certificates of analysis (CoA), and maintain transparent communication. Factors to consider include:

  • Quality Control: Look for suppliers with established QC protocols and certifications relevant to pharmaceutical intermediates.
  • Purity Levels: Ensure the specified purity meets your synthesis requirements.
  • Production Capacity: Verify the manufacturer's ability to meet your volume needs, whether for R&D or commercial production.
  • Pricing and Lead Times: Compare prices and delivery schedules from different suppliers to find the best value and ensure timely receipt of materials.
  • Regulatory Compliance: Confirm the supplier adheres to relevant industry standards and can provide necessary regulatory documentation.

Sourcing Strategies and Market Insights

The global market for pharmaceutical intermediates is competitive. Sourcing from established Chinese manufacturers often provides a cost advantage without compromising on quality. By conducting thorough due diligence on potential suppliers and requesting samples for evaluation, buyers can make informed decisions. Understanding market trends and the availability of key intermediates like 5-Acetylsalicylamide is crucial for strategic procurement. For those aiming to secure a dependable supply, exploring options to get a competitive quote from reputable China-based entities is a logical step.

In summary, procuring 5-Acetylsalicylamide requires careful consideration of quality, application suitability, and supplier reliability. By focusing on these aspects and leveraging the benefits of sourcing from experienced manufacturers and suppliers, particularly those in China, buyers can ensure the successful and cost-effective production of essential pharmaceutical products.