Procuring 6-Hydroxy-3,4-dihydro-1H-quinolin-2-one: A Buyer's Guide
Procurement professionals in the chemical and pharmaceutical sectors face the constant challenge of identifying and securing high-quality raw materials and intermediates. 6-Hydroxy-3,4-dihydro-1H-quinolin-2-one, identified by its CAS number 54197-66-9, is a prime example of such a critical compound. Its primary utility as a pharmaceutical intermediate, particularly in the synthesis of Cilostazol, necessitates a clear understanding of its specifications and sourcing channels.
For effective procurement, it's vital to be aware of the compound's key characteristics. 6-Hydroxy-3,4-dihydro-1H-quinolin-2-one is typically supplied as a white to tan powder or crystalline solid, boasting a melting point range of 236-240°C. Its molecular formula, C9H9NO2, and molecular weight of 163.17 are standard benchmarks. Crucially for R&D and manufacturing, purity levels, commonly assessed by HPLC, often exceed 95%, ensuring its suitability for sensitive chemical processes.
The compound's application as a key intermediate in the synthesis of Cilostazol, a drug for intermittent claudication, highlights its importance in the pharmaceutical supply chain. Moreover, its role as a metabolite of Cilostazol adds value for researchers investigating drug metabolism and pharmacokinetics. When looking to buy this chemical, procurement managers should prioritize suppliers who can guarantee consistent quality and batch-to-batch reproducibility.
When searching for a reliable supplier or manufacturer, particularly within the competitive Chinese market, it is advisable to solicit multiple quotes to compare pricing. Factors such as minimum order quantities, lead times, and the availability of necessary documentation (e.g., Certificates of Analysis, MSDS) should be carefully evaluated. Establishing a strong relationship with a trusted chemical provider ensures a steady supply of this essential intermediate, thereby supporting efficient production and research timelines. The strategic procurement of 6-Hydroxy-3,4-dihydro-1H-quinolin-2-one is a critical step in a successful pharmaceutical manufacturing process.
Perspectives & Insights
Quantum Pioneer 24
“6-Hydroxy-3,4-dihydro-1H-quinolin-2-one, identified by its CAS number 54197-66-9, is a prime example of such a critical compound.”
Bio Explorer X
“Its primary utility as a pharmaceutical intermediate, particularly in the synthesis of Cilostazol, necessitates a clear understanding of its specifications and sourcing channels.”
Nano Catalyst AI
“For effective procurement, it's vital to be aware of the compound's key characteristics.”