For procurement managers and R&D chemists in the chemical, pharmaceutical, and agrochemical sectors, the efficient sourcing of specialized intermediates is a critical factor for success. 3-Chloro-5-(trifluoromethyl)pyridin-2-amine (CAS No. 79456-26-1) is one such intermediate, highly valued for its utility in creating complex molecules. This guide aims to provide insight into its applications and how to secure a reliable supply.

Understanding the Intermediate: 3-Chloro-5-(trifluoromethyl)pyridin-2-amine

This compound is a substituted pyridine, characterized by a chlorine atom at the 3-position, an amine group at the 2-position, and a trifluoromethyl group at the 5-position of the pyridine ring. Its molecular formula is C6H4ClF3N2, and its CAS number is 79456-26-1. The trifluoromethyl group is particularly significant, as it often imparts enhanced lipophilicity, metabolic stability, and altered electronic properties to target molecules, making it invaluable in drug design and the development of effective agrochemicals.

When considering a purchase, key specifications to look for include its appearance (typically a white to light yellow crystalline powder) and purity, which is often specified as ≥98% by GC. Understanding these technical details is crucial for ensuring the intermediate will perform as expected in your synthesis protocols.

Key Applications and Market Demand

The demand for 3-Chloro-5-(trifluoromethyl)pyridin-2-amine stems from its broad applicability:

  • Pharmaceutical Synthesis: It acts as a crucial building block for synthesizing novel active pharmaceutical ingredients (APIs) with improved therapeutic profiles.
  • Agrochemical Development: It is integral to the creation of advanced pesticides, herbicides, and fungicides, contributing to crop protection and yield enhancement.
  • Organic Synthesis Research: Its reactive sites make it a versatile substrate for exploring new synthetic methodologies and creating complex organic structures.

The growing needs in these sectors translate to a steady demand for this intermediate. Therefore, identifying a consistent and dependable supplier is paramount for ongoing projects and manufacturing.

How to Buy: Navigating the Supply Chain

When you need to buy 3-Chloro-5-(trifluoromethyl)pyridin-2-amine, consider the following:

  • Manufacturer vs. Distributor: Direct sourcing from a manufacturer often provides better pricing and more direct quality control.
  • Purity Specifications: Always verify that the product meets the required purity levels for your application.
  • Bulk Quantities: For larger projects, inquire about bulk pricing and packaging options.
  • Supplier Reliability: Look for suppliers with a proven track record, excellent customer service, and comprehensive technical support.

We, as a specialized chemical manufacturer and supplier, are dedicated to meeting these needs. We offer high-purity 3-Chloro-5-(trifluoromethyl)pyridin-2-amine and are equipped to handle both research-scale and bulk orders. We invite you to contact us to discuss your specific requirements and to learn more about our competitive pricing and the quality assurance we provide. Secure your supply chain with a trusted partner.