For procurement managers and R&D scientists in the pharmaceutical and biotechnology sectors, the consistent availability of high-quality chemical intermediates is non-negotiable. Boc-(S)-3-Amino-3-(3-fluorophenyl)propionic Acid is one such compound that has gained significant traction due to its utility in peptide synthesis and drug discovery. This article serves as a guide for those looking to understand its importance and efficiently source it.

What is Boc-(S)-3-Amino-3-(3-fluorophenyl)propionic Acid?

This molecule is a derivative of the amino acid phenylalanine, specifically modified with a tert-butyloxycarbonyl (Boc) protecting group on the amine and a fluorine atom at the meta-position of the phenyl ring. The Boc group is essential for controlling reactivity during multi-step syntheses, especially in solid-phase peptide synthesis (SPPS), ensuring that reactions occur at the desired sites. The 3-fluorophenyl group introduces unique physicochemical properties that can enhance a compound's interaction with biological targets, improve its metabolic stability, and alter its lipophilicity, all crucial factors in drug design.

Key Applications Driving Demand

The demand for Boc-(S)-3-Amino-3-(3-fluorophenyl)propionic Acid is primarily driven by its role in:

  • Peptide-based Therapeutics: Incorporation into peptide sequences to enhance stability, efficacy, and targeting capabilities.
  • Small Molecule Drug Design: As a building block for synthesizing novel small molecules with potential activity against various diseases, including neurological disorders and cancer.
  • Medicinal Chemistry Research: Investigating structure-activity relationships and optimizing lead compounds.

When considering where to buy Boc-(S)-3-Amino-3-(3-fluorophenyl)propionic Acid, it's important to look for suppliers who offer high purity (often ≥99% by HPLC) and provide necessary documentation.

Finding a Reliable Supplier and Manufacturer

Procurement professionals often weigh the Boc-(S)-3-Amino-3-(3-fluorophenyl)propionic Acid price against quality and supply reliability. Identifying a reputable Boc-(S)-3-Amino-3-(3-fluorophenyl)propionic Acid manufacturer in China or elsewhere is key. Look for suppliers who:

  • Clearly state product specifications, including purity levels and analytical methods (e.g., HPLC).
  • Offer competitive pricing without compromising quality.
  • Have a robust supply chain and inventory management.
  • Provide excellent customer service and technical support.

Engaging with a trusted Boc-(S)-3-Amino-3-(3-fluorophenyl)propionic Acid supplier ensures your R&D projects have the essential components they need to succeed. By prioritizing quality and reliability, procurement can significantly contribute to the efficiency and success of drug development programs.