Procuring High-Purity (1S)-3-(dimethylamino)-1-(2-thienyl)propan-1-ol,(2S)-2-hydroxy-2-phenylacetic acid: A Buyer's Guide
For research scientists and procurement managers in the pharmaceutical and fine chemical industries, sourcing specialized intermediates like (1S)-3-(dimethylamino)-1-(2-thienyl)propan-1-ol,(2S)-2-hydroxy-2-phenylacetic acid (CAS 287737-72-8) requires a strategic approach. This compound, vital for the synthesis of important pharmaceuticals, necessitates careful consideration of purity, supply stability, and cost when making a purchase decision.
The primary application of this intermediate is its role as a precursor in the synthesis of Duloxetine hydrochloride, a widely used medication. The precise stereochemical configuration of CAS 287737-72-8 is critical for the efficacy of the final active pharmaceutical ingredient (API). Therefore, any buyer must prioritize suppliers who can guarantee high enantiomeric purity and consistent quality across batches. When searching for this product, common queries include 'buy (1S)-3-(dimethylamino)-1-(2-thienyl)propan-1-ol,(2S)-2-hydroxy-2-phenylacetic acid' or 'CAS 287737-72-8 price.'
As a global hub for chemical manufacturing, China offers numerous suppliers for this intermediate. However, differentiating between them requires diligence. Buyers should look for manufacturers with established quality control systems, certifications, and a proven track record in producing pharmaceutical intermediates. Detailed product specifications, including molecular formula (C17H23NO4S), molecular weight (337.43400), and appearance, should be readily available and verifiable. For instance, a reputable supplier will clearly indicate if the product is a solid or a specific physical form, although this specific compound's appearance is not explicitly stated in all datasheets, emphasizing the need for clear communication with the manufacturer.
When considering a purchase, potential buyers should also inquire about packaging options, storage recommendations, and lead times for delivery. For bulk orders or contract manufacturing, clear communication regarding production capacity and quality assurance protocols is essential. Establishing a relationship with a manufacturer that understands the regulatory landscape of pharmaceutical raw materials is highly advantageous. This includes their ability to provide necessary documentation and support for your specific region's import requirements.
In summary, procuring CAS 287737-72-8 involves more than just finding a seller. It's about partnering with a reliable manufacturer that can consistently deliver high-quality material, support your R&D efforts, and contribute to the efficient production of vital pharmaceuticals. Exploring options from reputable Chinese manufacturers and requesting detailed quotes will help secure the best value and ensure the integrity of your drug development pipeline.
Perspectives & Insights
Silicon Analyst 88
“Exploring options from reputable Chinese manufacturers and requesting detailed quotes will help secure the best value and ensure the integrity of your drug development pipeline.”
Quantum Seeker Pro
“For research scientists and procurement managers in the pharmaceutical and fine chemical industries, sourcing specialized intermediates like (1S)-3-(dimethylamino)-1-(2-thienyl)propan-1-ol,(2S)-2-hydroxy-2-phenylacetic acid (CAS 287737-72-8) requires a strategic approach.”
Bio Reader 7
“This compound, vital for the synthesis of important pharmaceuticals, necessitates careful consideration of purity, supply stability, and cost when making a purchase decision.”