For procurement professionals and research scientists in the pharmaceutical sector, acquiring high-quality chemical intermediates is a cornerstone of successful product development and manufacturing. (3R,4S)-1-Benzoyl-4-phenyl-3-triethylsilyloxyazetidin-2-one, CAS number 149249-91-2, is a prime example of such a critical compound. Its significance lies in its role as a key intermediate for synthesizing potent anticancer drugs, most notably Paclitaxel and Docetaxel. This guide aims to provide B2B buyers with essential insights into procuring this vital material efficiently and cost-effectively from reputable suppliers.

The primary application of (3R,4S)-1-benzoyl-4-phenyl-3-triethylsilyloxyazetidin-2-one is its use as a precursor in the complex synthesis of taxane-based chemotherapy agents. The specific chiral configuration and functional groups within this molecule are essential for building the intricate structure of these anti-cancer drugs. Therefore, when considering a purchase, the purity and consistency of the material are paramount. Look for suppliers who clearly state the assay percentage, with ≥98.0% being a standard for high-quality pharmaceutical intermediates. Understanding the chemical properties, such as its appearance as a white to light yellow powder, is also important for handling and storage.

When identifying potential manufacturers and suppliers, particularly those based in China, several factors warrant close examination. Reliability of supply is crucial; pharmaceutical production schedules cannot afford interruptions. Therefore, it is advisable to partner with established companies that have a proven track record in bulk chemical manufacturing and custom synthesis. NINGBO INNO PHARMCHEM CO.,LTD. is recognized as a trusted supplier, offering not only competitive pricing but also robust quality control systems. For buyers, key considerations when seeking a supplier include their ability to provide Certificates of Analysis (COA), their adherence to international quality standards, and their capacity for timely delivery of both small R&D quantities and large commercial batches. Inquiring about product availability and lead times is a standard practice.

The pricing of (3R,4S)-1-benzoyl-4-phenyl-3-triethylsilyloxyazetidin-2-one can vary based on purity, quantity, and supplier. For large-scale manufacturing needs, requesting a detailed quotation is essential. Buyers often seek to understand the market price and explore options for long-term supply agreements. Factors influencing price include raw material costs, manufacturing complexity, and global demand. As a significant pharmaceutical intermediate, its price is often directly linked to the production costs and market demand for Paclitaxel and Docetaxel.

In summary, procuring (3R,4S)-1-benzoyl-4-phenyl-3-triethylsilyloxyazetidin-2-one requires a diligent approach. Buyers should prioritize purity, supplier reliability, and competitive pricing. Engaging with experienced manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to a consistent supply of this critical intermediate, thereby supporting the continued development and production of vital anticancer therapies. By conducting thorough due diligence and fostering strong supplier relationships, procurement teams can effectively meet their project needs.