For pharmaceutical companies and contract manufacturing organizations (CMOs), the procurement of high-quality intermediates is paramount to successful drug development and production. (2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic Acid tert-butyl Ester, identified by CAS number 401564-36-1, stands out as a critical building block, particularly in the synthesis of Dipeptidyl Peptidase IV (DPP-IV) inhibitors like Teneligliptin. Understanding the nuances of sourcing this complex molecule is key for any procurement manager or R&D scientist.

When you search to buy this crucial pharmaceutical intermediate, several factors should guide your decision. Firstly, purity is non-negotiable. Intermediates with high purity levels, typically exceeding 98%, ensure cleaner reactions, higher yields, and ultimately, a safer and more effective final API. Manufacturers often provide Certificates of Analysis (COA) detailing purity, which is essential for regulatory compliance and process validation.

Secondly, consider the manufacturer's capabilities and reputation. A reputable supplier in China, like NINGBO INNO PHARMCHEM CO., LTD., offers not just competitive price, but also a commitment to consistent quality and stable supply. These attributes are vital for maintaining production schedules and managing inventory effectively. Look for suppliers who can provide comprehensive documentation, including Material Safety Data Sheets (MSDS) and Method of Analysis (MOA), to support your internal quality checks and regulatory filings.

The synthesis of Teneligliptin involves intricate chemical transformations, and the quality of the starting materials directly impacts the final product. (2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic Acid tert-butyl Ester (CAS 401564-36-1) acts as a key fragment, incorporating specific stereochemistry and functional groups necessary for the biological activity of Teneligliptin. Therefore, ensuring its correct structure and enantiomeric purity is critical.

When evaluating potential suppliers, inquire about their production capacity, lead times, and their adherence to Good Manufacturing Practices (GMP), if applicable to intermediates. For businesses looking to purchase this intermediate in bulk, negotiating favorable terms and establishing a long-term partnership with a reliable manufacturer can significantly reduce costs and mitigate supply chain risks. Exploring options for obtaining a sample before committing to a large order is also a prudent step.

In conclusion, for R&D scientists and procurement professionals focused on bringing innovative pharmaceutical products to market, the careful selection of a supplier for intermediates like (2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidinecarboxylic Acid tert-butyl Ester (CAS 401564-36-1) is a strategic imperative. Partner with a trusted pharmaceutical intermediate manufacturer to ensure the quality, consistency, and cost-effectiveness of your critical raw materials.