For professionals in the pharmaceutical, fine chemical, and research sectors, the consistent availability of high-quality chemical intermediates is paramount. L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid (L-Tic), identified by CAS 74163-81-8, is one such compound, recognized for its utility in synthesizing critical drug molecules and as a building block in advanced organic chemistry. This guide aims to assist you in the procurement of L-Tic, highlighting key specifications and sourcing considerations.

Understanding L-Tic: Properties and Applications

L-Tic is a chiral amino acid derivative that features a tetrahydroisoquinoline core. Its structure is particularly important in:

  • Pharmaceutical Synthesis: It is a crucial intermediate in the production of Quinapril, an ACE inhibitor used for treating cardiovascular conditions. The stereochemical purity of L-Tic directly influences the therapeutic efficacy of Quinapril.
  • Peptide Synthesis: As a non-natural amino acid, L-Tic can be incorporated into peptide sequences to confer specific conformational properties, enhance stability, or modulate biological activity. It's valuable for creating complex peptide structures and peptidomimetics.
  • Organic Synthesis: Its unique structure makes it a versatile chiral building block for a wide range of custom synthesis projects and the development of novel chemical entities.

The typical appearance of L-Tic is a white to off-white solid or powder, with a purity level often exceeding 97%. Its precise stereochemistry is vital, demanding careful control during manufacturing.

Key Considerations When Purchasing L-Tic

When you decide to buy L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid, several factors are critical to ensure you receive a product that meets your needs:

  • Purity Specifications: Always look for suppliers who provide detailed Certificates of Analysis (CoA) confirming purity levels and enantiomeric excess (ee%). This is essential for pharmaceutical intermediates.
  • Supplier Reputation: Choose manufacturers and suppliers with a proven track record in producing and supplying fine chemicals and pharmaceutical intermediates. A supplier's commitment to quality control and customer service is key.
  • Regulatory Compliance: Ensure the supplier can provide necessary documentation and operates under quality management systems that align with industry standards, especially for pharmaceutical applications.
  • Supply Chain Stability: For ongoing projects, a consistent and reliable supply is essential. Inquire about production capacity, lead times, and inventory levels.
  • Technical Support: Responsive technical assistance can be invaluable when working with specialized chemical intermediates.

As a dedicated manufacturer of high-quality chemical intermediates, we offer L-Tic with guaranteed purity and consistent supply. We understand the critical nature of this compound for pharmaceutical synthesis and research. We encourage you to contact us to inquire about purchasing L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid, request a sample, and obtain a competitive quote. Our expertise as a China-based manufacturer ensures you receive reliable materials for your demanding applications.

By carefully selecting your supplier, you can ensure the success of your synthetic pathways and research objectives, leveraging the unique properties of L-Tic with confidence.