For research and development scientists in the chemical and pharmaceutical sectors, the availability of specialized building blocks is fundamental to innovation. N-Boc-piperidine-4-sulfonyl chloride, also known by its CAS number 782501-25-1 and often referred to as Tert-butyl 4-(chlorosulfonyl)piperidine-1-carboxylate, is one such critical intermediate. Its unique chemical structure makes it highly valuable for creating complex organic molecules. This guide aims to assist R&D scientists in efficiently procuring this compound, focusing on quality, utility, and sourcing from reliable manufacturers.

N-Boc-piperidine-4-sulfonyl chloride is prized for its dual functionality. The Boc-protected piperidine ring offers a stable scaffold that can be further functionalized. Crucially, the sulfonyl chloride group (-SO₂Cl) serves as an electrophilic center, readily reacting with nucleophiles to form sulfonamides, sulfonates, and other sulfur-containing linkages. These motifs are prevalent in many classes of drugs, making this intermediate indispensable for medicinal chemistry and the synthesis of novel APIs. Scientists often search for terms like 'N-Boc-piperidine-4-sulfonyl chloride for sale' or 'buy Tert-butyl 4-(chlorosulfonyl)piperidine-1-carboxylate' when initiating new synthetic projects.

The quality of any chemical intermediate directly impacts the success of a synthesis. For R&D purposes, achieving high purity is paramount to avoid side reactions and ensure accurate characterization of final products. Therefore, when seeking to purchase this compound, it is essential to partner with reputable suppliers who can guarantee high purity (e.g., ≥97%) and provide thorough analytical documentation, such as Nuclear Magnetic Resonance (NMR) and High-Performance Liquid Chromatography (HPLC) data. These specifications are routinely confirmed by quality-conscious manufacturers worldwide.

Finding a reliable source often involves exploring chemical databases and supplier directories. Companies specializing in pharmaceutical intermediates and building blocks are prime targets. Many Chinese chemical manufacturers are prominent suppliers, offering competitive pricing, particularly for larger quantities. For R&D needs, smaller quantities are typically available. It’s beneficial to compare quotes from multiple vendors to secure the best possible price and lead time for your project timeline. Engaging directly with manufacturers allows for a deeper understanding of their production capabilities and quality control measures.

In summary, N-Boc-piperidine-4-sulfonyl chloride is a highly functional intermediate that can significantly advance R&D efforts in pharmaceutical and chemical synthesis. By understanding its chemical utility and employing a diligent approach to sourcing from qualified suppliers and manufacturers, scientists can ensure the availability of this crucial building block, thereby accelerating their discovery and development processes.