For procurement professionals in the pharmaceutical and chemical industries, the reliable sourcing of high-quality intermediates is a cornerstone of successful operations. 4-(4-Fluorophenyl)piperidine (CAS: 37656-48-7) is one such critical intermediate, widely used in drug synthesis. This buyer's guide provides essential information for procurement teams looking to acquire this compound effectively.

Understanding the Product: 4-(4-Fluorophenyl)piperidine

Chemical Identity: 4-(4-Fluorophenyl)piperidine
CAS Number: 37656-48-7
Molecular Formula: C11H14FN
Molecular Weight: 179.23 g/mol
Purity: Typically required at 99% for pharmaceutical applications.

This compound serves as a vital building block, providing a fluorinated piperidine scaffold essential for the development of numerous Active Pharmaceutical Ingredients (APIs). Its specific structure allows for diverse chemical modifications, making it a versatile intermediate in medicinal chemistry.

Key Considerations for Buyers

When procuring 4-(4-Fluorophenyl)piperidine, buyers should focus on several key aspects:

  1. Purity Specifications: Confirm that the supplier can consistently deliver the required purity, usually 99%. Request detailed Certificates of Analysis (CoA) for each batch.
  2. Supply Capacity: Assess the supplier's production capacity and supply ability. For industrial needs, robust manufacturers capable of producing hundreds of tons with a solid supply chain (e.g., 50 tons) are preferable.
  3. Packaging and Delivery: Inquire about standard packaging options (e.g., 25kg/drum, 200kg/drum) and available transportation methods (Ocean, Land, Air) from ports like Shanghai or Qingdao.
  4. Commercial Terms: Understand payment terms (L/C, T/T, etc.), Incoterms (FOB, CIF, etc.), and minimum order quantities (e.g., from 10 Grams for R&D to bulk quantities).

Evaluating Suppliers: The Advantage of Chinese Manufacturers

Chinese manufacturers have become leading suppliers of fine chemicals globally, offering a combination of competitive pricing, high production volumes, and technical expertise. When seeking to purchase 4-(4-Fluorophenyl)piperidine, buyers often find that Chinese suppliers provide:

  • Cost-Effective Solutions: Access to competitively priced intermediates without compromising quality.
  • Scalable Production: Manufacturers with proven capacity to meet both small-scale R&D and large-scale industrial demands.
  • Reliable Logistics: Efficient export and global shipping capabilities from major Chinese ports.

It is advisable to work with suppliers who provide clear product descriptions, prompt quotations, and are responsive to inquiries. Direct engagement with manufacturers allows for better communication and potential for customized solutions or long-term supply agreements.

How to Obtain a Quote

To get a quote for 4-(4-Fluorophenyl)piperidine, buyers should:

  • Identify potential suppliers, ideally reputable manufacturers in China.
  • Specify the required quantity (e.g., kilograms, tons).
  • Clearly state the purity requirement (e.g., 99%).
  • Inquire about lead times for production and delivery.
  • Request a formal quotation that outlines pricing, payment terms, and delivery details.

By following these guidelines, procurement professionals can efficiently source 4-(4-Fluorophenyl)piperidine, ensuring the continuity and quality of their pharmaceutical development and manufacturing processes. Partnering with a reliable manufacturer is key to a stable and cost-effective supply chain.