For chemists and researchers working with pharmaceutical intermediates and fine chemicals, understanding the intrinsic properties of a compound is fundamental to its successful application. 1,4-Dioxane-2,5-diol (CAS 23147-58-2), also known by its common name Glycolaldehyde Dimer, is no exception. Its physical and chemical characteristics dictate its handling, storage, and suitability for various synthetic pathways.

Physical Characteristics: Appearance and Form

1,4-Dioxane-2,5-diol typically presents as a White Crystalline Powder. This solid form is generally stable under recommended storage conditions, making it relatively easy to handle and measure in laboratory settings. The crystalline nature often indicates a good level of purity, which is crucial for its use as a pharmaceutical intermediate. If you are looking to buy, this appearance is a good initial indicator of quality.

Key Chemical and Physical Properties:

  • CAS Number: 23147-58-2 - This unique identifier is essential for accurate sourcing and referencing.
  • Molecular Formula: C4H8O4 - This formula reveals its composition and molecular weight.
  • Molecular Weight: Approximately 120.104 g/mol - Important for stoichiometric calculations in synthesis.
  • Melting Point: The reported melting point for 1,4-Dioxane-2,5-diol is around ~85 °C (some sources may indicate a range of 80-90 °C due to stereoisomeric composition). This relatively moderate melting point is characteristic of many organic crystalline solids.
  • Boiling Point: Approximately 312.4 ± 42.0 °C at 760 mmHg. This high boiling point suggests low volatility at ambient temperatures.
  • Density: Around 1.5 g/cm³. This density figure is useful for volumetric calculations and material handling.
  • Solubility: It exhibits limited solubility in water, described as 0.1 g/mL, and is generally considered clear and colorless in aqueous solutions. Its solubility in organic solvents will vary and is an important consideration for reaction media selection.
  • Purity: Typically specified at 99%, this high purity is critical for its application as a pharmaceutical intermediate.

Storage and Handling Recommendations

Based on its properties, 1,4-Dioxane-2,5-diol is often recommended for storage at temperatures between 2-8 °C (refrigerated). Proper storage helps maintain its stability and purity over time, ensuring its efficacy when you need to purchase and use it for your synthesis projects.

Understanding these properties empowers chemists to effectively integrate 1,4-Dioxane-2,5-diol into their synthetic schemes. When you are ready to buy this compound, consulting the supplier's detailed product specification sheet will provide the most accurate and up-to-date information, ensuring successful outcomes in your laboratory or manufacturing processes.