Understanding the Properties of 2-Chloro-4-methoxypyrimidine (CAS 22536-63-6)
For chemists, researchers, and procurement specialists in the pharmaceutical and agrochemical industries, a thorough understanding of chemical properties is fundamental to successful application and sourcing. 2-Chloro-4-methoxypyrimidine (CAS 22536-63-6) is a significant heterocyclic intermediate whose characteristics dictate its utility. As a leading Chinese manufacturer and supplier, we aim to provide clarity on these properties and how they benefit our B2B clients.
Key Physical Properties
When you buy 2-Chloro-4-methoxypyrimidine, you will typically receive it as a white powder. This physical form is standard for many fine chemical intermediates, facilitating accurate weighing and handling in laboratory and production settings. Its melting point is a critical parameter for identification and purity assessment, generally falling within the range of 54-57°C. This solid state at room temperature, combined with its moderate melting point, makes it practical for storage and use.
Chemical Structure and Reactivity
With the molecular formula C5H5ClN2O and a molecular weight of 144.56, 2-Chloro-4-methoxypyrimidine features a pyrimidine ring substituted with a chlorine atom at the 2-position and a methoxy group at the 4-position. This arrangement confers specific reactivity. The chlorine atom is an excellent leaving group, susceptible to nucleophilic substitution reactions with a variety of nucleophiles, such as amines, alcohols, and thiols. This reactivity is what makes it such a valuable intermediate in synthesizing more complex molecules, including pharmaceuticals and agrochemicals. The methoxy group can also influence the electron density of the pyrimidine ring, affecting its reactivity in other types of transformations.
Purity and Handling Considerations
As a dedicated supplier, we emphasize the importance of purity. Our 2-Chloro-4-methoxypyrimidine is typically offered with purities of 97% or 98%, ensuring reliable performance in demanding synthetic applications. Proper handling and storage are also crucial. While generally considered stable, it should be stored in a cool, dry place, away from direct light and incompatible materials. Understanding these properties helps ensure the longevity and efficacy of the compound when used in your research or manufacturing processes.
Reliable Sourcing from China
For B2B customers, sourcing this intermediate from a trusted Chinese manufacturer provides access to consistent quality and competitive pricing. We ensure our product meets the specifications required by the industry. If you are planning to purchase 2-Chloro-4-methoxypyrimidine or require further technical information, please do not hesitate to contact us. Our team is ready to assist you with your inquiries and to provide samples or quotes for your specific needs.
Perspectives & Insights
Agile Reader One
“Chemical Structure and Reactivity With the molecular formula C5H5ClN2O and a molecular weight of 144.”
Logic Vision Labs
“56, 2-Chloro-4-methoxypyrimidine features a pyrimidine ring substituted with a chlorine atom at the 2-position and a methoxy group at the 4-position.”
Molecule Origin 88
“The chlorine atom is an excellent leaving group, susceptible to nucleophilic substitution reactions with a variety of nucleophiles, such as amines, alcohols, and thiols.”