Understanding the Properties of 2-Chloro-4-nitrobenzoic Acid (CAS 99-60-5)
For professionals in chemical manufacturing and research, a thorough understanding of a compound's properties is fundamental to its successful application. 2-Chloro-4-nitrobenzoic acid (CAS 99-60-5) is a key organic intermediate, and its specific characteristics dictate its utility in various synthetic processes. As a reputable supplier, we aim to provide comprehensive insights into this valuable chemical.
Physically, 2-Chloro-4-nitrobenzoic acid typically presents as a light yellow to light green crystalline powder. This appearance is consistent across many batches, indicating a stable crystalline structure. Its melting point, generally reported in the range of 136-140°C, is a critical parameter for quality control and for determining its behavior during chemical reactions that involve heating. A sharp melting point within this range signifies high purity.
In terms of solubility, 2-Chloro-4-nitrobenzoic acid exhibits limited solubility in water, approximately 1 g/L at 20°C. This characteristic is common for aromatic organic acids with electron-withdrawing substituents. However, it is generally soluble in organic solvents such as ethanol, acetone, and ether, which are frequently used as reaction media in its synthetic applications. Understanding its solubility profile is crucial for designing effective reaction conditions and purification protocols.
Chemically, the compound is an aromatic carboxylic acid. The presence of the chlorine atom and the nitro group on the benzene ring influences its reactivity. The nitro group, being strongly electron-withdrawing, deactivates the ring towards electrophilic aromatic substitution but can be readily reduced to an amino group, a common transformation in organic synthesis. The carboxylic acid group can undergo standard reactions like esterification, amidation, or salt formation.
Manufacturers and researchers often need to buy 2-Chloro-4-nitrobenzoic acid for its role as a versatile building block. Its properties make it an ideal starting material for synthesizing pharmaceuticals, agrochemicals, dyes, and other fine chemicals. Ensuring the specified purity, as typically indicated by HPLC assay (often 97.5% min. or higher), is vital for achieving desired outcomes in complex syntheses.
As a dedicated chemical supplier, we provide detailed specifications for our 2-Chloro-4-nitrobenzoic acid, enabling our clients to make informed purchasing decisions. Whether you are looking to buy for research purposes or large-scale industrial production, understanding these properties is the first step towards successful application. Our commitment is to deliver a product that meets your precise requirements, backed by reliable technical information.
Perspectives & Insights
Chem Catalyst Pro
“The presence of the chlorine atom and the nitro group on the benzene ring influences its reactivity.”
Agile Thinker 7
“The nitro group, being strongly electron-withdrawing, deactivates the ring towards electrophilic aromatic substitution but can be readily reduced to an amino group, a common transformation in organic synthesis.”
Logic Spark 24
“The carboxylic acid group can undergo standard reactions like esterification, amidation, or salt formation.”