For chemists and researchers engaged in complex organic synthesis, a deep understanding of the properties of their starting materials and intermediates is fundamental to achieving successful and reproducible outcomes. 3-Amino-4-bromobenzonitrile, identified by its CAS number 72635-78-0, is a prime example of such a critical intermediate. Its physical and chemical characteristics dictate its reactivity and suitability for various synthetic pathways. At NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer and supplier, we prioritize clear communication of these properties to our clients.

Key Physical and Chemical Properties

3-Amino-4-bromobenzonitrile is typically encountered as a white to off-white crystalline solid, with a melting point around 99°C. This solid form makes it relatively easy to handle and weigh for reactions. The molecular formula, C7H5BrN2, indicates a molecular weight of approximately 197.03 g/mol. Its solubility varies depending on the solvent, but it is generally soluble in common organic solvents used in synthesis, such as DMF, DMSO, and potentially alcohols or ethers to varying degrees. The density is predicted to be around 1.68 g/cm³.

Reactivity and Synthetic Utility

The true value of 3-Amino-4-bromobenzonitrile lies in its inherent reactivity, driven by its functional groups:

  • Amino Group (-NH2): Readily participates in nucleophilic reactions, amide formation, and can be a site for further functionalization.
  • Bromine Atom (-Br): An excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira), allowing for the introduction of diverse carbon fragments.
  • Nitrile Group (-CN): Can be transformed into carboxylic acids, amides, amines, or used in constructing heterocyclic rings like tetrazoles.

These properties make it a cornerstone intermediate for building complex molecular structures, particularly in the synthesis of pharmaceuticals and fine chemicals. When you buy 3-amino-4-bromobenzonitrile, understanding these reactive sites is key to planning your synthetic routes.

Sourcing Considerations and Our Commitment

When you need to purchase 3-amino-4-bromobenzonitrile, it is essential to source from a reliable supplier in China. NINGBO INNO PHARMCHEM CO.,LTD. ensures that our product meets high purity standards (≥97%) and provides detailed technical documentation. We offer competitive 3-amino-4-bromobenzonitrile price points and are dedicated to ensuring the consistent quality required for your demanding synthesis projects. Our role as a direct manufacturer allows us to maintain strict quality control and offer dependable supply chain solutions.

We encourage researchers and procurement specialists to reach out to us to discuss their specific needs for 3-Amino-4-bromobenzonitrile. Our team is ready to provide the necessary technical information and ensure your sourcing requirements are met with efficiency and expertise.